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    Items where Author is "Dowling, Paul"


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    Number of items: 40.

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    Ting, Kay Reen and Henry, Michael and Meiller, Justine and Larkin, Annemarie and Clynes, Martin and Meleady, Paula and Bazou, Despina and Dowling, Paul and O'Gorman, Peter (2017) Novel panel of protein biomarkers to predict response to bortezomib-containing induction regimens in multiple myeloma patients. BBA Clinical, 8. pp. 28-34. ISSN 2214-6474

    Kavanagh, E.L. and Lindsay, S. and Halasz, M. and Gubbins, L.C. and Weiner-Gorzel, K. and Guang, M.H.Z. and McGoldrick, A. and Collins, E. and Henry, M. and Blanco-Fernández, A. and O'Gorman, Peter and Fitzpatrick, P. and Higgins, M.J. and Dowling, Paul and McCann, A. (2017) Protein and chemotherapy profiling of extracellular vesicles harvested from therapeutic induced senescent triple negative breast cancer cells. Oncogenesis, 6. e388. ISSN 2157-9024

    Hmmier, Abduladim and O'Brien, Michael Emmet and Lynch, Vincent and Clynes, Martin and Morgan, Ross and Dowling, Paul (2017) Proteomic analysis of bronchoalveolar lavage fluid (BALF) from lung cancer patients using label-free mass spectrometry. BBA Clinical, 7. pp. 97-104. ISSN 2214-6474

    Murphy, Sandra and Dowling, Paul and Zweyer, Margit and Henry, Michael and Meleady, Paula and Mundegar, Rustam R. and Swandulla, Dieter and Ohlendieck, Kay (2017) Proteomic profiling of mdx-4cv serum reveals highly elevated levels of the inflammation-induced plasma marker haptoglobin in muscular dystrophy. International Journal of Molecular Medicine, 39 (6). pp. 1357-1370. ISSN 1791-244X

    O'Sullivan, Dermot and Dowling, Paul and Joyce, Helena and McAuley, Edel and McCann, Andrew and Henry, Michael and McGovern, Brianan and Barham, Paul and Kelleher, Fergal C. and Murphy, Jean and Kennedy, Susan and Swan, Niall and Moriarty, Michael and Clynes, Martin and Larkin, Annemarie (2017) A novel inhibitory anti-invasive MAb isolated using phenotypic screening highlights AnxA6 as a functionally relevant target protein in pancreatic cancer. British Journal of Cancer, 117 (9). pp. 1326-1335. ISSN 1532-1827

    O'Sullivan, Dermot and Henry, Michael and Joyce, Helena and Walsh, Naomi and Mc Auley, Edel and Dowling, Paul and Swan, Niall and Moriarty, Michael and Barnham, Paul and Clynes, Martin and Larkin, Annemarie (2014) 7B7: a novel antibody directed against the Ku70/Ku80 heterodimer blocks invasion in pancreatic and lung cancer cells. Tumor Biology, 35 (7). pp. 6983-6997. ISSN 1010-4283

    Holland, Ashling and Schmitt-John, Thomas and Dowling, Paul and Meleady, Paula and Henry, Michael and Clynes, Martin and Ohlendieck, Kay (2014) Intricate effects of primary motor neuronopathy on contractile proteins and metabolic muscle enzymes as revealed by label-free mass spectrometry. Bioscience Reports, 34 (4). pp. 331-343. ISSN 1573-4935

    Dowling, Paul and Holland, Ashling and Ohlendieck, Kay (2014) Mass Spectrometry-Based Identification of Muscle-Associated and Muscle-Derived Proteomic Biomarkers of Dystrophinopathies. Journal of Neuromuscular Diseases, 1 (1). pp. 15-40. ISSN 2214-3599

    Holland, Ashling and Dowling, Paul and Ohlendieck, Kay (2014) New pathobiochemical insights into dystrophinopathy from the proteomics of senescent mdx mouse muscle. Frontiers in Aging Neuroscience, 6 (109). pp. 1-5. ISSN 1663-4365

    McDermott, Martina S.J. and Browne, Brigid C. and Conlon, Neil T. and O'Brien, Neil A. and Slamon, Dennis J. and Henry, Michael and Meleady, Paula and Clynes, Martin and Dowling, Paul and Crown, John and O'Donovan, Norma (2014) PP2A inhibition overcomes acquired resistance to HER2 targeted therapy. Molecular Cancer, 13 (157). pp. 1-12. ISSN 1476-4598

    Jockusch, Harald and Holland, Ashling and Staunton, Lisa and Schmitt-John, Thomas and Heimann, Peter and Dowling, Paul and Ohlendieck, Kay (2014) Pathoproteomics of testicular tissue deficient in the GARP component VPS54: The wobbler mouse model of globozoospermia. Proteomics, 14 (7-8). pp. 839-852. ISSN 1615-9853

    Holland, Ashling and Dowling, Paul and Zweyer, Margit and Swandulla, Dieter and Henry, Michael and Clynes, Martin and Ohlendieck, Kay (2013) Proteomic profiling of cardiomyopathic tissue from the aged mdx model of Duchenne muscular dystrophy reveals a drastic decrease in laminin, nidogen and annexin. Proteomics, 13 (15). pp. 2312-2323. ISSN 1615-9853

    Dowling, Paul and Clarke, Colin and Hennessy, Kim and Torralbo-Lopez, Beatriz and Ballot, Jo and Crown, John and Kiernan, Ingrid and O'Byrne, Kenneth J. and Kennedy, M. John and Lynch, Vincent and Clynes, Martin (2012) Analysis of acute-phase proteins, AHSG, C3, CLI, HP and SAA, reveals distinctive expression patterns associated with breast, colorectal and lung cancer. International Journal of Cancer, 131 (4). pp. 911-923. ISSN 0020-7136

    O'Connell, Kathleen and Prencipe, Maria and O'Neill, Amanda and Corcoran, Claire and Rani, Sweta and Henry, Michael and Dowling, Paul and Meleady, Paula and O'Driscoll, Lorraine and Watson, William and O'Connor, Robert (2012) The use of LC-MS to identify differentially expressed proteins in docetaxel-resistant prostate cancer cell lines. Proteomics, 12 (13). pp. 2115-2126. ISSN 1615-9853

    Egan, Brendan and Dowling, Paul and O'Connor, Paul L. and Henry, Michael and Meleady, Paula and Zierath, Juleen R. and O'Gorman, Donal J. (2011) 2-D DIGE analysis of the mitochondrial proteome from human skeletal muscle reveals time coursedependent remodelling in response to 14 consecutive days of endurance exercise training. Proteomics, 11 (8). pp. 1413-1428. ISSN 1615-9853

    Eustace, Alex J. and Dowling, Paul and Henry, Michael and Doolan, Padraig and Meleady, Paula and Clynes, Martin and Crown, John and O'Donovan, Norma (2011) 2D-DIGE analysis of phospho-enriched fractions from dasatinib-treated melanoma cell lines. Journal of Proteomics, 74 (4). pp. 490-501. ISSN 1874-3919

    Dowling, Paul and Clynes, Martin (2011) Conditioned media from cell lines: A complementary model to clinical specimens for the discovery of diseasespecific biomarkers. Proteomics, 11 (4). pp. 794-804. ISSN 1615-9853

    Walsh, Naomi and Larkin, Annemarie and Swan, Niall and Conlon, Kevin and Dowling, Paul and McDermott, Ray and Clynes, Martin (2011) RNAi knockdown of Hop (Hsp70/Hsp90 organising protein) decreases invasion via MMP-2 down regulation. Cancer Letters, 306 (2). pp. 180-189. ISSN 0304-3835

    Rajpal, Rajesh and Dowling, Paul and Meiller, Justine and Clarke, Colin and Murphy, William G. and O'Connor, Robert and Kell, Malcolm and Mitsiades, Constantine and Richardson, Paul and Anderson, Kenneth C. and Clynes, Martin and O'Gorman, Peter (2011) A novel panel of protein biomarkers for predicting response to thalidomide-based therapy in newly diagnosed multiple myeloma patients. Proteomics, 11 (8). pp. 1391-1402. ISSN 1615-9853

    Walsh, Naomi and O'Donovan, Norma and Kennedy, Susan and Henry, Michael and Meleady, Paula and Clynes, Martin and Dowling, Paul (2009) Identification of pancreatic cancer invasion-related proteins by proteomic analysis. Proteome Science, 7 (3). ISSN 1477-5956

    Muniyappa, M.K. and Dowling, Paul and Henry, M. and Meleady, Paula and Doolan, P. and Gammell, P. and Clynes, Martin and Barron, N. (2009) MiRNA-29a regulates the expression of numerous proteins and reduces the invasiveness and proliferation of human carcinoma cell lines. European Journal of Cancer, 45 (17). pp. 3104-3118. ISSN 0959-8049

    Walsh, Naomi and Dowling, Paul and O'Donovan, Norma and Henry, Michael and Meleady, Paula and Clynes, Martin (2008) Aldehyde dehydrogenase 1A1 and gelsolin identified as novel invasion-modulating factors in conditioned medium of pancreatic cancer cells. Journal of Proteomics, 71 (5). pp. 561-571. ISSN 1874-3919

    Dowling, Paul and Wormald, Robert and Meleady, Paula and Henry, Michael and Curran, Aongus and Clynes, Martin (2008) Analysis of the saliva proteome from patients with head and neck squamous cell carcinoma reveals differences in abundance levels of proteins associated with tumour progression and metastasis. Journal of Proteomics, 71 (2). pp. 168-175. ISSN 1874-3919

    Dowling, Paul and Walsh, Naomi and Clynes, Martin (2008) Membrane and membrane-associated proteins involved in the aggressive phenotype displayed by highly invasive cancer cells. Proteomics, 8 (19). pp. 4054-4065. ISSN 1615-9853

    Kumar, Niraj and Maurya, Priyanka and Gammell, Patrick and Dowling, Paul and Clynes, Martin and Meleady, Paula (2008) Proteomic Profiling of Secreted Proteins from CHO Cells Using Surface-Enhanced Laser Desorption Ionization Time-of-Flight Mass Spectrometry. Biotechnology Progress, 24 (1). pp. 273-278. ISSN 8756-7938

    Dowling, Paul and Shields, William and Rani, Sweta and Meleady, Paula and Henry, Michael and Jeppesen, Per Bendix and O'Driscoll, Lorraine and Clynes, Martin (2008) Proteomic analysis of conditioned media from glucose responsive and glucose nonresponsive phenotypes reveals a panel of secreted proteins associated with beta cell dysfunction. Electrophoresis, 29 (20). pp. 4141-4149. ISSN 0173-0835

    Dowling, Paul and O'Driscoll, Lorraine and Meleady, Paula and Henry, Michael and Roy, Shunil and Ballot, Jo and Moriarty, Michael and Crown, John and Clynes, Martin (2007) 2-D difference gel electrophoresis of the lung squamous cell carcinoma versus normal sera demonstrates consistent alterations in the levels of ten specific proteins. Electrophoresis, 28 (23). pp. 4302-4310. ISSN 0173-0835

    Dowling, Paul and Meleady, Paula and Dowd, Andrew and Henry, Michael and Glynn, Sharon and Clynes, Martin (2007) Proteomic analysis of isolated membrane fractions from superinvasive cancer cells. Biochimica et Biophysica Acta - Proteins and Proteomics, 1774 (1). pp. 93-101. ISSN 1570-9639

    Dowling, Paul and Maurya, Priyanka and Meleady, Paula and Glynn, Sharon and Dowd, Andrew and Henry, Michael and Clynes, Martin (2007) Purification and Identification of a 7.6-kDa Protein in Media Conditioned by Superinvasive Cancer Cells. Anticancer Research, 27 (3A). pp. 1309-1317. ISSN 0250-7005

    Doran, Philip and Martin, Geraldine and Dowling, Paul and Jockusch, Harald and Ohlendieck, Kay (2006) Proteome analysis of the dystrophin-deficient MDX diaphragm reveals a drastic increase in the heat shock protein cvHSP. Proteomics, 6 (16). pp. 4610-4621. ISSN 1615-9853

    Dowling, Paul and O'Driscoll, Lorraine and O'Sullivan, Finbarr and Dowd, Andrew and Henry, Michael and Jeppesen, Per Bendix and Meleady, Paula and Clynes, Martin (2006) Proteomic screening of glucose-responsive and glucose non-responsive MIN-6 beta cells reveals differential expression of proteins involved in protein folding, secretion and oxidative stress. Proteomics, 6 (24). pp. 6578-6587. ISSN 1615-9853

    Doran, Philip and Dowling, Paul and Donoghue, Pamela and Buffini, Maria and Ohlendieck, Kay (2006) Reduced expression of regucalcin in young and aged mdx diaphragm indicates abnormal cytosolic calcium handling in dystrophin-deficient muscle. Biochimica et Biophysica Acta - Proteins and Proteomics, 1764 (4). pp. 773-785. ISSN 1570-9639

    Donoghue, Pamela and Doran, Philip and Dowling, Paul and Ohlendieck, Kay (2005) Differential expression of the fast skeletal muscle proteome following chronic low-frequency stimulation. Biochimica et Biophysica Acta - Proteins and Proteomics, 1752 (2). pp. 166-176. ISSN 1570-9639

    Dowling, Paul and Doran, Philip and Ohlendieck, Kay (2004) Drastic reduction of sarcalumenin in Dp427 (dystrophin of 427 kDa)-deficient fibres indicates that abnormal calcium handling plays a key role in muscular dystrophy. Biochemical Journal, 379 (Pt.2). pp. 479-488. ISSN 0264-6021

    Dowling, Paul and Doran, Philip and Lohan, James and Culligan, Kevin and Ohlendieck, Kay (2004) Naturally Protected Muscle Phenotypes: Development of Novel Treatment Strategies for Duchenne Muscular Dystrophy. Basic and applied myology : BAM, 14 (3). pp. 169-177. ISSN 1120-9992

    Doran, Philip and Dowling, Paul and Lohan, James and McDonnell, Karen and Poetsch, Stephan and Ohlendieck, Kay (2004) Subproteomics analysis of Ca2+-binding proteins demonstrates decreased calsequestrin expression in dystrophic mouse skeletal muscle. European Journal of Biochemistry, 271 (19). pp. 3943-3952. ISSN 0014-2956

    Dowling, Paul and Lohan, James and Ohlendieck, Kay (2003) Comparative analysis of Dp427-deficient mdx tissues shows that the milder dystrophic phenotype of extraocular and toe muscle fibres is associated with a persistent expression of beta-dystroglycan. European Journal of Cell Biology, 82 (5). pp. 222-230. ISSN 0171-9335

    Dowling, Paul and Culligan, Kevin and Ohlendieck, Kay (2002) Distal mdx muscle groups exhibiting up-regulation of utrophin and rescue of dystrophin-associated glycoproteins exemplify a protected phenotype in muscular dystrophy. Naturwissenschaften, 89 (2). pp. 75-78. ISSN 0028-1042

    Culligan, Kevin and Banville, Niamh and Dowling, Paul and Ohlendieck, Kay (2002) Drastic reduction of calsequestrin-like proteins and impaired calcium binding in dystrophic mdx muscle. Journal of applied physiology, 92 (2). pp. 435-445. ISSN 8750-7587

    Culligan, Kevin and Glover, Louise and Dowling, Paul and Ohlendieck, Kay (2001) Brain dystrophin-glycoprotein complex: persistent expression of beta-dystroglycan, impaired oligomerization of Dp71 and up-regulation of utrophins in animal models of muscular dystrophy. BMC Cell Biology, 2 (2). ISSN 1471-2121

    This list was generated on Mon Nov 11 22:27:43 2019 UTC.