Article

Kealy, John, Murray, Carol, Griffin, Éadaoin W., Lopez-Rodriguez, Ana Belen, Healy, Dáire, Tortorelli, Lucas Silva, Lowry, John P., Watne, Leiv Otto and Cunningham, Colm (2020) Acute Inflammation Alters Brain Energy Metabolism in Mice and Humans: Role in Suppressed Spontaneous Activity, Impaired Cognition, and Delirium. The Journal of Neuroscience, 40 (29). pp. 5681-5696. ISSN 0270-6474

Gnahoré, Gama Theophile, Kelly, Jack L., O'Riordan, Saidhbhe L., Bolger, Fiachra B., Doran, Michelle M., Sands, Michelle and Lowry, John P. (2020) Development and validation of a real-time microelectrochemical sensor for clinical monitoring of tissue oxygenation/perfusion. Analytical Methods, 12 (19). pp. 2453-2459. ISSN 1759-9660

Baker, Keeley L., Bolger, Fiachra B., Doran, Michelle M. and Lowry, John P. (2018) Characterisation of a Platinum-based Electrochemical Biosensor for Real-time Neurochemical Analysis of Choline. Electroanalysis, 31 (1). pp. 129-136. ISSN 10400397

Tang, Zhengyuan, Barton, Sinead, Ward, Tomas E., Lowry, John P., Doran, Michelle M., Byrne, Hugh J. and Hennelly, Bryan M. (2018) Multicomponent analysis using a confocal Raman microscope. Applied Optics, 57 (22). ISSN 1559-128X

Tang, Zhengyuan, Barton, Sinead, Ward, Tomas E., Lowry, John P., Doran, Michelle M., Byrne, Hugh J. and Hennelly, Bryan M. (2018) Quantifying the concentration of glucose, urea, and lactic acid in aqueous mixtures by confocal Raman microscopy. Proceedings of SPIE, 10685. 106850V. ISSN 0277-786X

Kealy, John, Bennett, Rachel, Woods, Barbara and Lowry, John P. (2017) Real-time changes in hippocampal energy demands during a spatial working memory task. Behavioural Brain Research, 326. pp. 59-68. ISSN 0166-4328

Baker, Keeley L., Bolger, Fiachra B. and Lowry, John P. (2017) Development of a microelectrochemical biosensor for the real-time detection of choline. Sensors and Actuators B: Chemical, 243. pp. 412-420. ISSN 0925-4005

Teles-Grillo Ruivo, Leonor M., Baker, Keeley L., Conway, Michael W., Kinsley, Peter J., Gilmour, Gary, Phillips, Keith G., Isaac, John T.R., Lowry, John P. and Mellor, Jack R. (2017) Coordinated Acetylcholine Release in Prefrontal Cortex and Hippocampus Is Associated with Arousal and Reward on Distinct Timescales. Cell Reports, 18 (4). pp. 905-917.

O'Connor, John J., O'Boyle, K.M. and Lowry, John P. (2017) Effects of a combination of 3,4-methylenedioxymeth amphetamine and caffeine on real time stimulated dopamine release in the rat striatum: studies using fast cyclic voltammetry. Journal of Neuroscience Methods, 300. pp. 216-223. ISSN 0165-0270

O'Riordan, Saidhbhe L. and Lowry, John P. (2017) In vivo characterisation of a catalase-based biosensor for real-time electrochemical monitoring of brain hydrogen peroxide in freely-moving animals. Analytical Methods, 9. pp. 1253-1264. ISSN 1759-9660

Doran, Michelle M., Finnerty, Niall J. and Lowry, John P. (2017) In–Vitro Development and Characterisation of a Superoxide Dismutase-Based Biosensor. ChemistrySelect, 2 (14). pp. 4157-4164. ISSN 2365-6549

Kealy, John, Commins, Sean and Lowry, John P. (2017) The effect of NMDA-R antagonism on simultaneously acquired local field potentials and tissue oxygen levels in the brains of freely-moving rats. Neuropharmacology, 116. pp. 343-350. ISSN 1873-7064

Connor, John J. and Lowry, John P. (2016) A comparison of the effects of the dopamine partial agonists aripiprazole and (-)-3-PPP with quinpirole on stimulated dopamine release in the rat striatum: studies using fast cyclic voltammetry in vitro. European Journal of Pharmacology, 686 (1-3). pp. 60-65. ISSN 0014-2999

Francois, Jennifer, Huxter, John, Conway, Michael W., Lowry, John P., Tricklebank, Mark and Gilmour, Gary (2014) Differential Contributions of Infralimbic Prefrontal Cortex and Nucleus Accumbens during Reward-Based Learning and Extinction. The Journal of Neuroscience, 34 (2). pp. 596-607. ISSN 0270-6474

Barkus, Christopher, Line, Samantha J., Huber, Anna, Capitao, Liliana, Lima, Joao, Jennings, Katie, Lowry, John P., Sharp, Trevor, Bannerman, David M. and McHugh, Stephen B. (2014) Variation in Serotonin Transporter Expression Modulates FearEvoked Hemodynamic Responses and ThetaFrequency Neuronal Oscillations in the Amygdala. Biological Psychiatry, 75 (11). pp. 901-908. ISSN 0006-3223

Finnerty, Niall J., O'Riordan, Saidhbhe, Lowry, John P., Cloutier, Mathieu and Wellstead, Peter (2013) Continuous Real-Time in vivo Measurement of Cerebral Nitric Oxide Supports Theoretical Predictions of an Irreversible Switching in Cerebral ROS after Sufficient Exposure to External Toxins. Journal of Parkinson’s Disease, 3. pp. 351-362. ISSN 1877-7171

McHugh, Stephen B., Marques-Smith, Andre, Li, Jennifer, Rawlins, J.N.P., Lowry, John P., Conway, Michael W., Gilmour, Gary, Tricklebank, Mark and Bannerman, David M. (2013) Hemodynamic responses in amygdala and hippocampus distinguish between aversive and neutral cues during Pavlovian fear conditioning in behaving rats. European Journal of Neuroscience, 37. pp. 498-507. ISSN 0953-816X

Govindarajan, Sridhar, McNeil, Calum J., Lowry, John P., McMahon, Colm P. and O'Neill, Robert D. (2013) Highly selective and stable microdisc biosensors for l-glutamate monitoring. Sensors and Actuators B, 178. pp. 606-614. ISSN 0925-4005

Finnerty, Niall J., Bolger, Fiachra B., Pålsson, Erik and Lowry, John P. (2013) An Investigation of Hypofrontality in an Animal Model of Schizophrenia Using Real-Time Microelectrochemical Sensors for Glucose, Oxygen, and Nitric Oxide. ACS Chemical Neuroscience, 4. pp. 825-831. ISSN 1948-7193

Kealy, John, Bennett, Rachel and Lowry, John P. (2013) Simultaneous recording of hippocampal oxygen and glucose in real time using constant potential amperometry in the freely-moving rat. Journal of Neuroscience Methods, 215 (1). pp. 110-120.

Finnerty, Niall J., O'Riordan, Saidhbhe, Palsson, Erik and Lowry, John P. (2012) Brain nitric oxide: Regional characterisation of a real-time microelectrochemical sensor. Journal of Neuroscience Methods, 209 (1). pp. 13-21. ISSN 0165-0270

Francois, Jennifer, Conway, Michael W., Lowry, John P., Tricklebank, Mark and Gilmour, Gary (2012) Changes in reward-related signals in the rat nucleus accumbens measured by in vivo oxygen amperometry are consistent with fMRI BOLD responses in man. NeuroImage, 60 (4). pp. 2169-2181. ISSN 1053-8119

McHugh, Stephen B., Fillenz, Marianne, Lowry, John P., Rawlins, J.N.P. and Bannerman, David M. (2011) Brain tissue oxygen amperometry in behaving rats demonstrates functional dissociation of dorsal and ventral hippocampus during spatial processing and anxiety. European Journal of Neuroscience, 33. pp. 322-337. ISSN 0953-816X

Bolger, Fiachra B., McHugh, Stephen B., Bennett, Rachel, Li, J., Ishiwari, K., Francois, Jennifer, Conway, Michael W., Gilmour, Gary, Bannerman, David M., Fillenz, Marianne, Tricklebank, Mark and Lowry, John P. (2011) Characterisation of carbon paste electrodes for real-time amperometric monitoring of brain tissue oxygen. Journal of Neuroscience Methods, 195 (2). pp. 135-142. ISSN 0165-0270

Li, Jennifer, Bravo, Diego S., Upton, A. Louise, Gilmour, Gary, Tricklebank, Mark, Fillenz, Marianne, Martin, Chris, Lowry, John P., Bannerman, David M. and McHugh, Stephen B. (2011) Close temporal coupling of neuronal activity and tissue oxygen responses in rodent whisker barrel cortex. European Journal of Neuroscience, 34. pp. 1983-1996. ISSN 0953-816X

Finnerty, Niall J., O'Riordan, Saidhbhe, Brown, Finbar O., Serra, Pier A., O'Neill, Robert D. and Lowry, John P. (2011) In vivo characterisation of a Nafion®-modified Pt electrode for real-time nitric oxide monitoring in brain extracellular fluid. Analytical Methods, 4. pp. 550-557. ISSN 1759-9660

Bolger, Fiachra B., Bennett, Rachel and Lowry, John P. (2011) An in vitro characterisation comparing carbon paste and Pt microelectrodes for real-time detection of brain tissue oxygen. Analyst, 136 (19). pp. 4028-2035. ISSN 0003-2654

Lowry, John P., Griffin, Karen, McHugh, Stephen B., Lowe, Andrew S., Tricklebank, Mark and Sibson, Nicola R. (2010) Real-time electrochemical monitoring of brain tissue oxygen: A surrogate for functional magnetic resonance imaging in rodents. NeuroImage, 52 (2). pp. 549-555. ISSN 1053-8119

Zaina, Zainiharyati M., O'Neill, Robert D., Lowry, John P., Pierce, Kenneth W., Tricklebank, Mark, Dewae, Aidiahmad and Ab Ghani, Sulaiman (2010) Development of an implantable d-serine biosensor for in vivo monitoring using mammalian d-amino acid oxidase on a poly (o-phenylenediamine) and Nafion-modified platinum–iridium disk electrode. Biosensors and Bioelectronics, 25 (6). pp. 1454-1459. ISSN 0956-5663

Palsson, Erik, Lowry, John P. and Klamer, Daniel (2010) Information processing deficits and nitric oxide signalling in the phencyclidine model of schizophrenia. Psychopharmacology, 212 (4). pp. 643-651. ISSN 0033-3158

Lowry, John P. and Scanlan, John (2009) Blue Box sensors: Ireland's newest pharmaceutical devices company. Research : NUI Maynooth Research Magazine, 1 (2). pp. 18-19.

Fejgin, Kim, Palsson, Erik, Wass, Caroline, Finnerty, Niall J., Lowry, John P. and Klamer, Daniel (2009) Prefrontal GABAB Receptor Activation Attenuates Phencyclidine-Induced Impairments of Prepulse Inhibition: Involvement of Nitric Oxide. Neuropsychopharmacology, 34. pp. 1673-1684. ISSN 0893-133X

Cloutier, Mathieu, Bolger, Fiachra B., Lowry, John P. and Wellstead, Peter (2009) An integrative dynamic model of brain energy metabolism using in vivo neurochemical measurements. Journal of Computational Neuroscience. ISSN 0929-5313

Calia, Giammario, Rocchitta, Gaia, Migheli, Rossana, Puggioni, Giulia, Spissu, Ylenia, Bazzu, Gianfranco, Mazzarello, Vittorio, Lowry, John P., O'Neill, Robert D., Desole, Maria S. and Serra, Pier A. (2009) Biotelemetric Monitoring of Brain Neurochemistry in Conscious Rats Using Microsensors and Biosensors. Sensors, 9 (4). pp. 2511-2523. ISSN 1424-8220

Sibson, Nicola R., McHugh, S. and Lowry, John P. (2009) Combined fMRI and metabolic voltammetry in vivo: understanding the neurochemical basis of functional imaging signals. Journal of Cerebral Blood Flow & Metabolism, 29 (1_Supp). pp. 613-614. ISSN 0271-678X

Rothwell, Sharon A., Kinsella, Michael E., Zaina, Zainiharyati M., Serra, Pier A., Rocchitta, Gaia, Lowry, John P. and O'Neill, Robert D. (2009) Contributions by a Novel Edge Effect to the Permselectivity of an Electrosynthesized Polymer for Microbiosensor Applications. Analytical Chemistry, 81 (10). pp. 3911-3918. ISSN 0003-2700

AL Mulla, Ismael, Lowry, John P., Serra, Pier A. and O'Neill, Robert D. (2009) Development of a voltammetric technique for monitoring brain dopamine metabolism: compensation for interference caused by DOPAC electrogenerated during homovanillic acid detection. Analyst, 134. pp. 893-898. ISSN 0003-2654

Palsson, Erik, Finnerty, Niall J., Fejgin, Kim, Klamer, Daniel, Wass, Caroline, Svensson, Lennart and Lowry, John P. (2009) Increased Cortical Nitric Oxide Release After Phencyclidine Administration. Synapse, 63. pp. 1083-1088. ISSN 1098-2396

Brown, Finbar O., Finnerty, Niall J. and Lowry, John P. (2009) Nitric oxide monitoring in brain extracellular fluid: characterisation of Nafion-modified Pt electrodes in vitro and in vivo. Analyst, 134 (10). pp. 2012-2020. ISSN 0003-2654

Bazzu, Gianfranco, Puggioni, Giulia, Dedola, Sonia, Calia, Giammario, Rocchitta, Gaia, Migheli, Rossana, Desole, Maria S., Lowry, John P., O'Neill, Robert D. and Serra, Pier A. (2009) Real-Time Monitoring of Brain Tissue Oxygen Using a Miniaturized Biotelemetric Device Implanted in Freely Moving Rats. Analytical Chemistry, 81 (6). pp. 2235-2241. ISSN 0003-2700

Earley, Sean T., Alcock, Bernadette E., Lowry, John P. and Breslin, Carmel B. (2009) Remediation of chromium(VI) at polypyrrole-coated titanium. Journal of Applied Electrochemistry, 39 (8). pp. 1251-1257. ISSN 0021-891X

O'Neill, Robert D., Rocchitta, Gaia, McMahon, Colm P., Serra, Pier A. and Lowry, John P. (2008) Designing sensitive and selective polymer/enzyme composite biosensors for brain monitoring in vivo. TrAC Trends in Analytical Chemistry, 27 (1). pp. 78-88. ISSN 0165-9936

Migheli, Rossana, Puggioni, Giulia, Dedola, Sonia, Rocchitta, Gaia, Calia, Giammario, Bazzu, Gianfranco, Esposito, Giovanni, Lowry, John P., O'Neill, Robert D., Desole, Maria S., Miele, Egidio and Serra, Pier A. (2008) Novel integrated microdialysis-amperometric system for in vitro detection of dopamine secreted from PC12 cells: design, construction, and validation. Analytical Biochemistry, 380 (2). pp. 323-330. ISSN 0003-2697

Kirwan, Sarah M., Rocchitta, Gaia, McMahon, Colm P., Craig, Jennifer D., Killoran, Sarah J., O'Brien, Kylie B., Serra, Pier A., Lowry, John P. and O'Neill, Robert D. (2007) Modifications of Poly(o-phenylenediamine) Permselective Layer on Pt-Ir for Biosensor Application in Neurochemical Monitoring. Sensors, 7 (4). pp. 420-437. ISSN 1424-8220

Serra, Pier A., Rocchitta, Gaia, Bazzu, Gianfranco, Manca, Antonio, Puggioni, Giulia, Lowry, John P. and O'Neill, Robert D. (2007) Design and construction of a low cost single-supply embedded telemetry system for amperometric biosensor applications. Sensors and Actuators B: Chemical, 122 (1). pp. 118-126. ISSN 0925-4005

O'Brien, Kylie B., Killoran, Sarah J., O'Neill, Robert D. and Lowry, John P. (2007) Development and characterization in vitro of a catalase-based biosensor for hydrogen peroxide monitoring. Biosensors and Bioelectronics, 22 (12). pp. 2994-3000. ISSN 0956-5663

Rocchitta, Gaia, Migheli, Rossana, Dedola, Sonia, Calia, Giammario, Desole, Maria S., Lowry, John P., O'Neill, Robert D. and Serra, Pier A. (2007) Development of a distributed, fully automated, bidirectional telemetry system for amperometric microsensor and biosensor applications. Sensors and Actuators B: Chemical, 126 (2). pp. 700-709. ISSN 0925-4005

McMahon, Colm P., Rocchitta, Gaia, Kirwan, Sarah M., Killoran, Sarah J., Serra, Pier A., Lowry, John P. and O'Neill, Robert D. (2007) Oxygen tolerance of an implantable polymer/enzyme composite glutamate biosensor displaying polycation-enhanced substrate sensitivity. Biosensors and Bioelectronics, 22 (7). pp. 1466-1473. ISSN 0956-5663

McMahon, Colm P., Rocchitta, Gaia, Serra, Pier A., Kirwan, Sarah, Lowry, John P. and O'Neill, Robert D. (2006) Control of the Oxygen Dependence of an Implantable Polymer/Enzyme Composite Biosensor for Glutamate. Analytical Chemistry, 78 (7). pp. 2352-2359. ISSN 0003-2700

Lowry, John P., Mc Mahon, Colm, Rocchitta, Gaia, Serra, Pier A., Kirwan, Sarah and O'Neill, Robert (2006) The efficiency of immobilised glutamate oxidase decreases with surface enzyme loading: an electrostatic effect, and reversal by a polycation significantly enhances biosensor sensitivity. Analyst, 131. pp. 68-72.

Bolger, Fiachra B. and Lowry, John P. (2005) Brain Tissue Oxygen: In Vivo Monitoring using Carbon Paste Electrodes. Sensors, 5 (11). pp. 473-487. ISSN 1424-8220

Brown, Finbar O., Finnerty, Niall J., Bolger, Fiachra B., Millar, Julian and Lowry, John P. (2005) Calibration of NO sensors for In Vivo Voltammetry: Laboratory synthesis of NO and the use of UV-visible spectroscopy in determining stock concentrations. Analytical and Bioanalytical Chemistry, 381 (4). pp. 964-971. ISSN 1618-2642

Earley, Sean T., Dowling, Dennis P., Lowry, John P. and Breslin, Carmel B. (2005) Formation of adherent polypyrrole coatings on Ti and Ti–6Al–4V alloy. Synthetic Metals, 148 (2). pp. 111-118. ISSN 0379-6779

O'Neill, Robert D., Chang, Seung-Cheol, Lowry, John P. and McNeil, Calum J. (2004) Comparisons of platinum, gold, palladium and glassy carbon as electrode materials in the design of biosensors for glutamate. Biosensors and Bioelectronics, 19 (11). pp. 1521-1528. ISSN 0956-5663

Lowry, John P. (2004) Monitoring Real-time Metabolite Trafficking in the Brain using Microelectrochemical Biosensors. MCFA Annals, 3. pp. 92-97.

Brown, Finbar O. and Lowry, John P. (2003) Microelectrochemical Sensors for In Vivo Brain Analysis: An Investigation of Procedures for Modifying Pt Electrodes Using Nafion®. Analyst, 128. pp. 700-705. ISSN 0003-2654

O'Connor, William T., O'Connor, John J., Lowry, John P. and O'Neill, Robert D. (2002) 9th International Conference on In Vivo Methods Monitoring Molecules in Neuroscience, June 16-19, 2001, University College Dublin, Ireland. Journal of Neuroscience Methods, 119 (2). pp. 105-107. ISSN 0165-0270

Dixon, Blanaid M., Lowry, John P. and O'Neill, Robert D. (2002) Characterization in vitro and in vivo of the oxygen dependence of an enzyme/polymer biosensor for monitoring brain glucose. Journal of Neuroscience Methods, 119 (2). pp. 135-142. ISSN 0165-0270

Lowry, John P. and Fillenz, Marianne (2001) Real-time monitoring of brain energy metabolism in vivo using microelectrochemical sensors: the effects of anesthesia. Bioelectrochemistry, 54 (1). pp. 39-47. ISSN 1567-5394

Fillenz, Marianne, Lowry, John P., Boutelle, M.G. and Fray, A.E. (1999) The role of astrocytes and noradrenaline in neuronal glucose metabolism. Acta Physiologica Scandinavica, 167 (4). pp. 275-284. ISSN 0001-6772

Lowry, John P., Ryan, Michael R. and O'Neill, Robert D. (1998) Behaviourally induced changes in ectracellular levels of brain glutamate monitored at 1 s resolution with an implanted biosensor. Analytical Communications, 35. pp. 87-89. ISSN 1359-7337

Lowry, John P., O'Neill, Robert D., Boutelle, M.G. and Fillenz, Marianne (1998) Continuous monitoring of extracellular glucose concentrations in the striatum of freely moving rats with an implanted glucose biosensor. Journal of Neurochemistry, 70 (1). pp. 391-396. ISSN 0022-3042

Lowry, John P., Miele, Maddalena, O'Neill, Robert D., Boutelle, M.G. and Fillenz, Marianne (1998) An amperometric glucose-oxidase/poly(o-phenylenediamine) biosensor for monitoring brain extracellular glucose: in vivo characterisation in the striatum of freely-moving rats. Journal of Neuroscience Methods, 79 (1). pp. 65-74. ISSN 0165-0270

Fillenz, Marianne and Lowry, John P. (1998) The relation between local cerebral blood flow and extracellular glucose concentration in rat striatum. Experimental Physiology, 83 (2). pp. 233-238. ISSN 0958-0670

Ryan, Michael R. and Lowry, John P. (1997) Biosensor for Neurotransmitter L-Glutamic Acid Designed for Efficient Use of L-Glutamate Oxidase and Effective Rejection of Interference. Analyst, 122. pp. 1419-1424. ISSN 0003-2654

Lowry, John P. and Fillenz, Marianne (1997) Evidence for uncoupling of oxygen and glucose utilization during neuronal activation in rat striatum. Journal of Physiology, 498 (2). pp. 497-501. ISSN 0022-3751

Lowry, John P., Boutelle, M.G. and Fillenz, Marianne (1997) Measurement of brain tissue oxygen at a carbon paste electrode can serve as an index of increases in regional cerebral blood flow. Journal of Neuroscience Methods, 71 (2). pp. 177-182. ISSN 0165-0270

Lowry, John P., McAteer, Karl, El Atrash, Satea S., Duff, Adrienne and O'Neill, Robert D. (1994) Characterization of glucose oxidase-modified poly(phenylenediamine)-coated electrodes in vitro and in vivo: Homogeneous interference by ascorbic acid in hydrogen peroxide detection. Analytical Chemistry, 66 (10). pp. 1754-1761. ISSN 0003-2700

Lowry, John P., McAteer, Karl, El Atrash, Satea S. and O'Neill, Robert D. (1994) Efficient glucose detection in anaerobic solutions using an enzyme-modified electrode designed to detect H2O2: Implications for biomedical applications. Journal of the Chemical Society, Chemical Communications, 21. pp. 2483-2484. ISSN 0022-4936

Book Section

Breslin, Carmel B. and Lowry, John P. (1999) Electrochemistry at NUI Maynooth. In: The Irish Scientist. Samton Limited, p. 138. ISBN 1898706182

Conference or Workshop Item

Valente, Sabrina, Ringwood, John, Mangourova, Violeta and Lowry, John P. (2012) Investigation of events in the EEG signal correlated with changes in both oxygen and glucose in the brain. In: ISSC 2012, 28-29 June, 2012, NUI Maynooth.