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Daumann, Lena J. and Dalle, Kristian E. and Schenk, Gerhard and McGeary, Ross P. and Bernhardt, Paul V. and Ollis, David L. and Gahan, Lawrence R. (2012) The role of Zn–OR and Zn–OH nucleophiles and the influence of para-substituents in the reactions of binuclear phosphatase mimetics. Dalton Transactions, 41. pp. 1695-1708. ISSN 1477-9226
Ugwumba, Isaac N. and Ozawa, Kiyoshi and Xu, Zhi-Qiang and Ely, Fernanda and Foo, Jee-Loon and Herlt, Anthony J. and Coppin, Chris and Brown, Sue and Taylor, Matthew C. and Ollis, David L. and Mander, Lewis N. and Schenk, Gerhard and Dixon, Nicholas E. and Otting, Gottfried and Oakeshott, John G. and Jackson, Colin J. (2011) Improving a Natural Enzyme Activity through Incorporation of Unnatural Amino Acids. Journal of the American Chemical Society, 133 (2). pp. 326-333. ISSN 0002-7863
Kantacha, Anob and Buchholz, Rebecca and Smith, Sarah J. and Schenk, Gerhard and Gahan, Lawrence R. (2011) Phosphate ester cleavage promoted by a tetrameric iron(III) complex. Journal of Biological Inorganic Chemistry, 16 (1). pp. 23-32. ISSN 0949-8257
Ely, Fernanda and Hadler, Kieran S. and Gahan, Lawrence R. and Guddat, Luke W. and Ollis, David L. and Schenk, Gerhard (2010) The organophosphate-degrading enzyme from Agrobacterium radiobacter displays mechanistic flexibility for catalysis. Biochemical Journal, 432 (3). pp. 565-573. ISSN 0264-6021
Mitic, Natasa and Hadler, Keiran S. and Gahan, Lawrence R. and Hengge, Alvan C. and Schenk, Gerhard (2010) The divalent metal ion in the active site of uteroferrin modulates substrate binding and catalysis. Journal of the American Chemical Society, 132 (20). pp. 7049-6054. ISSN 0002-7863
Neves, Ademir and Bortoluzzi, Adailton J. and Jovito, Rafael and Peralta, Rosely A. and de Souza, Bernardo and Szpoganicz, Bruno and Joussef, Antonio C. and Terenzi, Hernan and Severino, Patricia C. and Fischer, Franciele L. and Schenk, Gerhard and Riley, Mark J. and Smith, Sarah J. and Gahan, Lawrence R. (2010) Catalytic Promiscuity: Catecholase-like Activity and Hydrolytic DNA Cleavage Promoted by a Mixed-Valence FeIIIFeII Complex. Journal of the Brazilian Chemical Society, 21 (7). pp. 1201-1212. ISSN 0103-5053
Hadler, Kieran S. and Mitic, Natasa and Yip, Sylvia Hsu-Chen and Gahan, Lawrence R. and Ollis, David L. and Schenk, Gerhard and Larrabee, James A. (2010) Electronic Structure Analysis of the Dinuclear Metal Center in the Bioremediator Glycerophosphodiesterase (GpdQ) from Enterobacter aerogenes. Inorganic Chemistry, 49. pp. 2727-2734. ISSN 0020-1669
Peralta, Rosely A. and Bortoluzzi, Adailton J. and de Souza, Bernardo and Jovito, Rafael and Xavier, Fernando R. and Couto, Ricardo A. A. and Casellato, Annelise and Nome, Faruk and Dick, Andrew and Gahan, Lawrence R. and Schenk, Gerhard and Hanson, Graeme R. and de Paula, Flavia C. S. and Pereira-Maia, Elene C. and Machado, Sergio de P. and Severino, Patricia C. and Pich, Claus and Bortolotto, Tiago and Terenzi, Hernan and Castellano, Eduardo E. and Neves, Ademir and Riley, Mark J. (2010) Electronic Structure and Spectro-Structural Correlations of FeIIIZnII Biomimetics for Purple Acid Phosphatases: Relevance to DNA Cleavage and Cytotoxic Activity. Inorganic Chemistry, 49. pp. 11421-11438. ISSN 0020-1669
Foo, Jee-Loon and Jackson, Colin J. and Carr, Paul D. and Kim, Hye-Kyung and Schenk, Gerhard and Gahan, Lawrence R. and Ollis, David L. (2010) Mutation of outer-shell residues modulates metal ion co-ordination strength in a metalloenzyme. Biochemistry Journal, 429. pp. 313-321.
Lessa, Josane A. and Horn Jr., Adolfo and Bull, Erika S. and Rocha, Michelle R. and Benassi, Mario and Catharino, Rodrigo R. and Eberlin, Marcos N. and Casellato, Annelise and Noble, Christopher J. and Hanson, Graeme R. and Schenk, Gerhard and Silva, Giselle C. and Antunes, O. A. C. and Fernandes, Christiane (2009) Catalase vs Peroxidase Activity of a Manganese(II) Compound: Identification of a Mn(III)-(μ-O)2-Mn(IV) Reaction Intermediate by Electrospray Ionization Mass Spectrometry and Electron Paramagnetic Resonance Spectroscopy. Inorganic Chemistry, 48 (10). pp. 4569-4579. ISSN 0020-1669
McGeary, Ross P. and Vella, Peter and Mak, Jeffrey Y. W. and Guddat, Luke W. and Schenk, Gerhard (2009) Inhibition of purple acid phosphatase with a-alkoxynaphthylmethylphosphonic acids. Bioorganic and Medicinal Chemistry Letters , 19. pp. 163-166. ISSN 0960-894X
Mitic, Natasa and Noble, Christopher J. and Gahan, Lawrence R. and Hanson, Graeme R. and Schenk, Gerhard (2009) Metal-Ion Mutagenesis: Conversion of a Purple Acid Phosphatase from Sweet Potato to a Neutral Phosphatase with the Formation of an Unprecedented Catalytically Competent MnIIMnII Active Site. Journal of the American Chemical Society, 131 (23). pp. 8173-8179. ISSN 0002-7863
Hadler, Kieran S. and Mitic, Natasa and Ely, Fernanda and Hanson, Graeme R. and Gahan, Lawrence R. and Larrabee, James A. and Ollis, David L. and Schenk, Gerhard (2009) Structural Flexibility Enhances the Reactivity of the Bioremediator Glycerophosphodiesterase by Fine-Tuning Its Mechanism of Hydrolysis. Journal of the American Chemical Society, 131 (33). pp. 11900-11908. ISSN 0002-7863
Smith, Sarah J. and Riley, Mark J. and Noble, Christopher J. and Hanson, Graeme R. and Stranger, Robert and Jayaratne, Vidura and Cavigliasso, German and Schenk, Gerhard and Gahan, Lawrence R. (2009) Structural and Catalytic Characterization of a Heterovalent Mn(II)Mn(III) Complex That Mimics Purple Acid Phosphatases. Inorganic Chemistry, 48. pp. 10036-10048. ISSN 0020-1669
Xavier, Fernando R. and Neves, Ademir and Casellato, Annelise and Peralta, Rosaly A. and Bortoluzzi, Adailton J. and Szpoganicz, Bruno and Severino, Patricia C. and Terenzi, Hernan and Tomkowicz, Zbigniew and Haase, Wolfgang and Ozarowski, Andrew and Krzystek, Jerzy and Telser, Joshua and Schenk, Gerhard and Gahan, Lawrence R. (2009) Unsymmetrical FeIIICoII and GaIIICoII Complexes as Chemical Hydrolases: Biomimetic Models for Purple Acid Phosphatases (PAPs). Inorganic Chemistry, 48. pp. 7905-7091. ISSN 0020-1669
Hadler, Kieran S. and Huber, Thomas and Cassady, A. Ian and Weber, Jane and Robinson, Jodie and Burrows, Allan and Kelly, Gregory and Guddat, Luke W. and Hume, David A. and Schenk, Gerhard and Flanagan, Jack U. (2008) Identification of a non-purple tartrate-resistant acid phosphatase: an evolutionary link to Ser/Thr protein phosphatases? BMC Research Notes, 1 (78). pp. 1-8. ISSN 1756-0500
Jackson, Colin J. and Hadler, Kieran S. and Carr, Paul D. and Oakley, Aaron J. and Yip, Sylvia and Schenk, Gerhard and Ollis, David L. (2008) Malonate-bound structure of the glycerophosphodiesterase from Enterobacter aerogenes (GpdQ) and characterization of the native Fe2+ metal-ion preference. Acta Crystallographica Section F, 64 (8). pp. 681-685. ISSN 1744-3091
Schenk, Gerhard and Elliott, Tristan W. and Leung, Eleanor and Carrington, Lyle E. and Mitic, Natasa and Gahan, Lawrence R. and Guddat, Luke W. (2008) Crystal structures of a purple acid phosphatase, representing different steps of this enzyme's catalytic cycle. BMC Structural Biology, 8 (6). doi:10.1186/1472-6807. ISSN 1472-6807
Buchholz, Rebecca and Etienne, Morgan E. and Dorgelo, Anneke and Mirams, Ruth E. and Smith, Sarah J. and Chow, Shiao Yun and Hanton, Lyall R. and Jameson, Geoffrey B. and Schenk, Gerhard and Gahan, Lawrence R. (2008) A structural and catalytic model for zinc phosphoesterases. Dalton Transactions, 43. pp. 6045-6054. ISSN 1477-9226
Schenk, Gerhard and Peralta, Rosely A. and Batista, Suzana Cimara and Bortoluzzi, Adailton J. and Szpoganicz, Bruno and Dick, Andrew J. and Herrald, Paul and Hanson, Graeme R. and Szilagyi, Robert K. and Riley, Mark J. and Gahan, Lawrence R. and Neves, Ademir (2008) Probing the role of the divalent metal ion in uteroferrin using metal ion replacement and a comparison to isostructural biomimetics. Journal of Biological Inorganic Chemistry, 13 (1). pp. 139-155. ISSN 0949-8257
Smith, S. J. and Noble, C. J. and Palmer, R. C. and Hanson, G. R. and Schenk, Gerhard and Gahan, L. R. and Riley, M. J. (2008) Structural and spectroscopic studies of a model for catechol oxidase. Journal of Biological Inorganic Chemistry, 13 (4). pp. 499-510. ISSN 0949-8257
Hadler, Kieran S. and Tanifum, Eric A. and Hsu-Chen Yip, Sylvia and Mitic, Natasa and Guddat, Luke W. and Jackson, Colin J. and Gahan, Lawrence R. and Nguyen, Kelly and Carr, Paul D. and Ollis, David L. and Hengge, Alvan C. and Larrabee, James A. and Schenk, Gerhard (2008) Substrate-Promoted Formation of a Catalytically Competent Binuclear Center and Regulation of Reactivity in a Glycerophosphodiesterase from Enterobacter aerogenes. Journal of the American Chemical Society, 130 (43). pp. 14129-14138. ISSN 0002-7863
Neves, Ademir and Lanznaster, Mauricio and Bortoluzzi, Adailton J. and Peralta, Rosely A. and Casellato, Annelise and Castellano, Eduardo Ernesto and Herrald, Paul and Riley, Mark J. and Schenk, Gerhard (2007) An Unprecedented FeIII(μ-OH)ZnII Complex that Mimics the Structural and Functional Properties of Purple Acid Phosphatases. Journal of the American Chemical Society, 129 (24). pp. 7486-7487. ISSN 0002-7863
Cox, Robynn S. and Schenk, Gerhard and Mitic, Natasa and Gahan, Lawrence R. and Hengge, Alvan C. (2007) Diesterase Activity and Substrate Binding in Purple Acid Phosphatases. Journal of the American Chemical Society, 129. pp. 9550-9551.
Neidig, Michael L. and Wecksler, Aaron T. and Schenk, Gerhard and Holman, Theodore R. and Solomon, Edward I. (2007) Kinetic and Spectroscopic Studies of N694C Lipoxygenase: A Probe of the Substrate Activation Mechanism of a Nonheme Ferric Enzyme. Journal of the American Chemical Society, 129. pp. 7531-7537. ISSN 0002-7863
Boudalis, Athanassios K. and Aston, Robyn E. and Smith, Sarah J. and Mirams, Ruth E. and Riley, Mark J. and Schenk, Gerhard and Blackman, Allan G. and Hanton, Lyall R. and Gahan, Lawrence R. (2007) Synthesis and characterization of the tetranuclear iron(III) complex of a new asymmetric multidentate ligand. A structural model for purple acid phosphatases. Dalton Transactions. pp. 5132-5139. ISSN 1477-9226
Liu, Jian-Wei and Hadler, Kieran S. and Schenk, Gerhard and Ollis, David (2007) Using directed evolution to improve the solubility of the C-terminal domain of Escherichia coli aminopeptidase P Implications for metal binding and protein stability. The FEBS Journal, 274 (18). pp. 4742-4751. ISSN 1742-464X
Jackson, Colin J. and Carr, Paul D. and Kim, Hye-Kyung and Liu, Jian-Wei and Herrald, Paul and Mitic, Natasa and Schenk, Gerhard and Smith, Clyde A. and Ollis, David L. (2006) Anomalous scattering analysis of Agrobacterium radiobacter phosphotriesterase: the prominent role of iron in the heterobinuclear active site. Biochemical Journal, 397. pp. 501-508. ISSN 0264-6021
Elliott, Tristan W. and Mitic, Natasa and Gahan, Lawrence R. and Guddat, Luke W. and Schenk, Gerhard (2006) Inhibition Studies of Purple Acid Phosphatases: Implications for the Catalytic Mechanism. Journal of the Brazilian Chemical Society, 17 (8). pp. 1558-1565. ISSN 0103-5053
Mitic, Natasa and Smith, Sarah J. and Neves, Ademir and Guddat, Luke W. and Gahan, Lawrence R. and Schenk, Gerhard (2006) The Catalytic Mechanisms of Binuclear Metallohydrolases. Chemical Reviews, 106 (8). pp. 3338-3363. ISSN 0009-2665
Schenk, Gerhard and Gahan, Lawrence R. and Carrington, Lyle E. and Mitic, Natasa and Valizadeh, Mohsen and Hamilton, Susan E. and de Jersey, John and Guddat, Luke W. (2005) Phosphate forms an unusual tripodal complex with the Fe–Mn center of sweet potato purple acid phosphatase. Proceedings of the National Academy of Sciences , 102 (2). pp. 273-278. ISSN 1091-6490
Lanznaster, Mauricio and Neves, Ademir and Bortoluzzi, Adailton J. and Aires, Veronika V. E. and Szpoganicz, Bruno and Terenzi, Hernan and Cardoso Severino, Patricia and Fuller, Julie M. and Drew, Simon C. and Gahan, Lawrence R. and Hanson, Graeme R. and Riley, Mark J. and Schenk, Gerhard (2005) A New Heterobinuclear FeIIICuII Complex with a Single Terminal FeIII–O(phenolate) Bond. Relevance to Purple Acid Phosphatases and Nucleases. Journal of Biological Inorganic Chemistry, 10 (4). pp. 319-332. ISSN 0949-8257
Lanznaster, Mauricio and Neves, Ademir and Bortoluzzi, Adailton J. and Aires, Veronika V. E. and Szpoganicz, Bruno and Terenzi, Hernan and Severino, Patricia C. and Fuller, Julie M. and Drew, Simon C. and Gahan, Lawrence R. and Hanson, Graeme R. and Riley, Mark J. and Schenk, Gerhard (2005) A New Heterobinuclear FeIIICuII Complex with a Single Terminal FeIII–O(phenolate) Bond. Relevance to Purple Acid Phosphatases and Nucleases. Journal of Biological Inorganic Chemistry, 10 (4). pp. 319-332. ISSN 0949-8257
Schenk, Gerhard and Pau, Monita Y. M. and Solomon, Edward I. (2004) Comparison between the Geometric and Electronic Structures and Reactivities of {FeNO}7 and {FeO2}8 Complexes: A Density Functional Theory Study. Journal of the American Chemical Society, 126 (2). pp. 505-515. ISSN 0002-7863
Bernhardt, Paul V. and Schenk, Gerhard and Wilson, Gregory J. (2004) Direct Electrochemistry of Porcine Purple Acid Phosphatase (Uteroferrin). Biochemistry, 43. pp. 10387-10392. ISSN 0006-2960
Valizadeh, Mohsen and Schenk, Gerhard and Nash, Kevin and Oddie, Geoff W. and Guddat, Luke W. and Hume, David A. and de Jersey, John and Burke Jr., Terrence R. and Hamilton, Susan E. (2004) Phosphotyrosyl peptides and analogues as substrates and inhibitors of purple acid phosphatases. Archives of Biochemistry and Biophysics , 424. pp. 154-162. ISSN 0003-9861
Mitic, Natasa and Saleh, Lana and Schenk, Gerhard and Bollinger, J. Martin Jr. and Solomon, Edward I. (2003) Rapid-Freeze-Quench Magnetic Circular Dichroism of Intermediate X in Ribonucleotide Reductase: New Structural Insight. Journal of the American Chemical Society, 125 (37). pp. 11200-11201. ISSN 0002-7863
Schenk, Gerhard and Neidig, Michael L. and Zhou, Jing and Holman, Theodore R. and Solomon, Edward I. (2003) Spectroscopic Characterization of Soybean Lipoxygenase-1 Mutants: the Role of Second Coordination Sphere Residues in the Regulation of Enzyme Activity. Biochemistry, 42 (24). pp. 7294-7302. ISSN 0006-2960
Twitchett, Mark B. and Schenk, Gerhard and Aquino, Manuel A. S. and Yiu, Douglas T.-Y. and Lau, Tai-Chu and Sykes, A. Geoffrey (2002) Reactivity of MII Metal-Substituted Derivatives of Pig Purple Acid Phosphatase (Uteroferrin) with Phosphate. Inorganic Chemistry, 41 (22). pp. 5787-5794. ISSN 0020-1669
Schenk, Gerhard and Boutchards, Clare and Carrington, Lyle E. and Noble, Christopher J. and Moubaraki, Boujemaa and Murray, Keith S. and de Jersey, John and Hanson, Graeme R. and Hamilton, Susan E. (2001) A Purple Acid Phosphatase from Sweet Potato Contains an Antiferromagnetically Coupled Binuclear Fe-Mn Center. Biochemistry, 276 (22). pp. 19084-19088. ISSN 0006-2960
Schenk, Gerhard and Guddat, L.W. and Ge, L. and Carrington, Lyle E. and Hume, D.A. and Hamilton, S.E. and de Jersey, J. (2000) Identification of mammalian-like purple acid phosphatases in a wide range of plants. Gene, 250. pp. 117-125. ISSN 0378-1119
Schenk, Gerhard and Korsinczky, Michael L.J. and Hume, David A. and Hamilton, Susan E. and de Jersey, John (2000) Purple acid phosphatases from bacteria: similarities to mammalian and plant enzymes. Gene, 255. pp. 419-424. ISSN 0378-1119
Oddie, G.W. and Schenk, Gerhard and Angel, N.Z. and Walsh, N. and Guddat, L.W. and de Jersey, J. and Cassady, A.I. and Hamilton, S.E. and Hume, D.A. (2000) Structure, Function, and Regulation of Tartrate-Resistant Acid Phosphatase. Bone, 27 (5). pp. 575-584. ISSN 8756-3282
Schenk, Gerhard and Ge, Yubin and Carrington, Lyle E. and Wynne, Ceridwen J. and Searle, Iain R. and Carroll, Bernard J. and Hamilton, Susan E. and de Jersey, John (1999) Binuclear Metal Centers in Plant Purple Acid Phosphatases: Fe-Mn in Sweet Potato and Fe-Zn in Soybean. Archives of Biochemistry and Biophysics , 370 (2). pp. 183-189. ISSN 0003-9861
Schenk, Gerhard and Carrington, Lyle E. and Hamilton, Susan E. and de Jersey, John and Guddat, Luke W. (1999) Crystallization and preliminary X-ray diffraction data for a purple acid phosphatase from sweet potato. Acta Crystallographica Section D Biological Crystallography, 55 (12). pp. 2051-2052. ISSN 0907-4449
Schenk, Gerhard and Duggleby, Ronald and Nixon, Peter (1998) Heterologous expression of human transketolase. The International Journal of Biochemistry & Cell Biology, 30. pp. 369-378. ISSN 1357-2725
Schenk, Gerhard and Layfield, Roy and Candy, Judith M. and Duggleby, Ronald G. and Nixon, Peter F. (1997) Molecular Evolutionary Analysis of the Thiamine-Diphosphate-Dependent Enzyme, Transketolase. Journal of Molecular Evolution , 44. pp. 552-572. ISSN 0022-2844
Schenk, Gerhard and Leeper, Finian J. and England, Renee and Nixon, Peter and Duggleby, Ronald (1997) The role of His113 and His114 in pyruvate decarboxylase from Zymomonas mobilis. European Journal of Biochemistry , 248. pp. 63-71. ISSN 0014-2956
Schenk, Gerhard and Duggleby, Ronald (1991) Properties and functions of the thiamin diphosphate dependent enzyme transketolase. The International Journal of Biochemistry & Cell Biology, 30. pp. 1297-1318. ISSN 1357-2725
