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Downes, Shane G. and Owens, Rebecca A. and Walshe, Kieran and Fitzpatrick, David A. and Dorey, Amber and Jones, Gary W. and Doyle, Sean (2023) Gliotoxin-mediated bacterial growth inhibition is caused by specific metal ion depletion. Scientific Reports, 13 (1). ISSN 2045-2322
Traynor, Aimee M. and Sarikaya-Bayram, Özlem and Bayram, Ozgur and Antonio Calera, José and Doyle, Sean (2023) Proteomic dissection of the role of GliZ in gliotoxin biosynthesis in Aspergillus fumigatus. Fungal Genetics and Biology, 166. p. 103795. ISSN 1087-1845
Smith, Helen and Doyle, Sean and Murphy, Richard (2023) Target directed identification of natural bioactive compounds from filamentous fungi. Food Chemistry, 405 (Part A). pp. 1-8. ISSN 0308-8146
Borges, Bruno Montanari and Ramos, Rafael Berton Correia and Preite, Nycolas Willian and Kaminski, Valéria de Lima and Alves de Castro, Patrícia and Camacho, Maurício and Maximo, Marina Ferreira and Fill, Taicia Pacheco and Calich, Vera Lúcia Garcia and Traynor, Aimee M. and Sarikaya-Bayram, Özlem and Doyle, Sean and Bayram, Ozgur and de Campos, Claudia Barbosa Ladeira and Zelanis, André and Goldman, Gustavo H. and Loures, Flávio Vieira (2023) Transcriptional profiling of a fungal granuloma reveals a low metabolic activity of Paracoccidioides brasiliensis yeasts and an actively regulated host immune response. Frontiers in Cellular and Infection Microbiology, 13. pp. 1-27. ISSN 2235-2988
Abdel-Moneim, Ahmed S. and Berre, Marie Le and Paulovčáková, Terézia and Verissimo, Carolina De Marco and Doyle, Sean and Dalton, John P. and Masterson, Claire and Martínez, Eduardo Ribes and Walsh, Laura and Gormley, Conor and Laffey, John G. and McNicholas, Bairbre and Simpkin, Andrew J. and Kilcoyne, Michelle (2023) A new multiplex SARS-CoV-2 antigen microarray showed correlation of IgG, IgA, and IgM antibodies from patients with COVID-19 disease severity and maintenance of relative IgA and IgM antigen binding over time. PLOS ONE, 18 (3). pp. 1-31. ISSN 1932-6203
Rawlings, Anna and O'Connor, Eoin and Moody, Suzy C. and Dudley, Ed and Boddy, Lynne and Fowler, Mike S. and Fitzpatrick, David A. and Doyle, Sean and Eastwood, Dan C. (2022) Metabolic responses of two pioneer wood decay fungi to diurnally cycling temperature. Journal of Ecology, 110 (1). pp. 68-79. ISSN 0022-0477
De Marco Verissimo, Carolina and López Corrales, Jesús and Dorey, Amber L. and Cwiklinski, Krystyna and Lalor, Richard and Calvani, Nichola Eliza Davies and Jewhurst, Heather L. and Flaus, Andrew and Doyle, Sean and Dalton, John P. (2022) Production of a functionally active recombinant SARS-CoV-2 (COVID-19) 3C-like protease and a soluble inactive 3C-like protease-RBD chimeric in a prokaryotic expression system. Epidemiology and Infection, 150. ISSN 0950-2688
Doyle, Sean and Cuskelly, Daragh D. and Conlon, Niall and Fitzpatrick, David A. and Gilmartin, Ciara B. and Dix, Sophia H. and Jones, Gary W. (2022) A Single Aspergillus fumigatus Gene Enables Ergothioneine Biosynthesis and Secretion by Saccharomyces cerevisiae. International Journal of Molecular Sciences, 23 (18). p. 10832. ISSN 1422-0067
Traynor, Aimee M. and Owens, Rebecca A. and Coughlin, Claudia M. and Holton, Maeve C. and Jones, Gary W. and Calera, José A. and Doyle, Sean (2021) At the metal–metabolite interface in Aspergillus fumigatus: towards untangling the intersecting roles of zinc and gliotoxin. Microbiology, 167 (11). ISSN 1350-0872
Traynor, Aimee M. and Owens, Rebecca A. and Coughlin, Claudia M. and Holton, Maeve C. and Jones, Gary W. and Calera, José A. and Doyle, Sean (2021) At the metal–metabolite interface in Aspergillus fumigatus: towards untangling the intersecting roles of zinc and gliotoxin. Microbiology, 167 (11). ISSN 1350-0872
Moloney, Nicola M. and Larkin, Annemarie and Xu, Linan and Fitzpatrick, David A. and Crean, Holly L. and Walshe, Kieran and Haas, Hubertus and Decristoforo, Clemens and Doyle, Sean (2021) Generation and characterisation of a semi-synthetic siderophore-immunogen conjugate and a derivative recombinant triacetylfusarinine C–specific monoclonal antibody with fungal diagnostic application. Analytical Biochemistry, 632. p. 114384. ISSN 0003-2697
De Marco Verissimo, Carolina and O'Brien, Carol and López Corrales, Jesús and Dorey, Amber and Cwiklinski, Krystyna and Lalor, Richard and Doyle, Jack M. and Field, Stephen and Masterson, Claire and Ribes Martinez, Eduardo and Hughes, Gerry and Bergin, Colm and Walshe, Kieran and McNicholas, Bairbre and Laffey, John G. and Dalton, John P. and Kerr, Colm and Doyle, Sean (2021) Improved diagnosis of SARS-CoV-2 by using nucleoprotein and spike protein fragment 2 in quantitative dual ELISA tests. Epidemiology and Infection, 149 (e140). pp. 1-11. ISSN 0950-2688
Xu, Linan and Zhang, Hong and Cuskelly, Daragh D. and Doyle, Sean and Perrett, Sarah and Jones, Gary W. (2021) Mutational analysis of the Hsp70 substrate‐binding domain: Correlating molecular‐level changes with in vivo function. Molecular Microbiology, 115 (6). pp. 1262-1276. ISSN 0950-382X
O'Connor, Eoin and Doyle, Sean and Amini, Aniça and Grogan, Helen and Fitzpatrick, David A. (2021) Transmission of mushroom virus X and the impact of virus infection on the transcriptomes and proteomes of different strains of Agaricus bisporus. Fungal Biology, 125 (9). pp. 704-717. ISSN 1878-6146
Ries, Laure Nocolas Annick and Pardeshi, Lakhansing and Dong, Zhiqiang and Tan, Kaeling and Steenwyk, Jacob L and Colabardini, Ana Christina and Ferreira Filho, Jaire A. and de Castro, Patricia A. and Silva, Lilian Pereira and Preite, Nycolas W and Almeida, Fausto and de Assis, Leandro J and dos Santos, Renato A C and Bowyer, Paul and Bromley, Michael and Owens, Rebecca A. and Doyle, Sean and Demasi, Marilene and Hernandez, Diego C R and Netto, Luis Eduardo S and Pupo, Monica T and Rokas, Antonis and Loures, Flavio V and Wong, Koon H and Goldman, Gustavo H (2020) The Aspergillus fumigatus transcription factor RglT is important for gliotoxin biosynthesis and self-protection, and virulence. PLOS Pathogens, 16 (7). e1008645. ISSN 1553-7366
O’Connor, Eoin and Owens, Rebecca A. and Doyle, Sean and Amini, Aniça and Grogan, Helen and Fitzpatrick, David A. (2020) Proteomic investigation of interhyphal interactions between strains of Agaricus bisporus. Fungal Biology, 124 (6). pp. 579-591. ISSN 18786146
Scott, Jennifer and Sueiro-Olivares, Monica and Thornton, Benjamin P and Owens, Rebecca A. and Muhamadali, Howbeer and Fortune-Grant, Rachael and Thomson, Darren and Thomas, Riba and Hollywood, Katherine and Doyle, Sean and Goodacre, Royston and Tabernero, Lydia and Bignell, Elaine and Amich, Jorge (2020) Targeting Methionine Synthase in a Fungal Pathogen Causes a Metabolic Imbalance That Impacts Cell Energetics, Growth, and Virulence. mBio, 11 (5). e01985-20. ISSN 2150-7511
Waldron, Rose and McGowan, Jamie and Gordon, Natasha and Mitchell, E Bruce and Fitzpatrick, David A. and Doyle, Sean (2019) Characterisation of three novel ß-1,3 glucanases from the medically important house dust mite Dermatophagoides pteronyssinus (airmid). Insect Biochemistry and Molecular Biology, 115 (103242). ISSN 0965-1748
Sarikaya-Bayram, Ozlem and Dettmann, Anne and Karahoda, Betim and Moloney, Nicola M. and Ormsby, Tereza and McGowan, Jamie and Cea-Sánchez, Sara and Miralles-Duran, Alejandro and Brancini, Guilherme T P and Luque, Eva and Fitzpatrick, David A. and Canovas, David and Corrochano, Luis M and Doyle, Sean and Selker, Eric U and Seiler, Stephen and Bayram, Ozgur (2019) Control of development, secondary metabolism and light-dependent carotenoid biosynthesis by the velvet complex of Neurospora crassa. Genetics, 212 (3). pp. 691-710. ISSN 0016-6731
Traynor, Aimee M and Sheridan, Kevin J and Jones, Gary W and Calera, José A and Doyle, Sean (2019) Involvement of Sulfur in the Biosynthesis of Essential Metabolites in Pathogenic Fungi of Animals, particularly Aspergillus spp.: Molecular and Therapeutic Implications. Frontiers in Microbiology, 10 (2859). ISSN 1664-302X
Xu, Linan and Nitika and Hasin, Naushaba and Cuskelly, Daragh and Wolfgeher, Donald and Doyle, Sean and Moynagh, Paul N. and Perrett, Sarah and Jones, Gary W. and Truman, Andrew W. (2019) Rapid deacetylation of yeast Hsp70 mediates the cellular response to heat stress. Scientific Reports, 9 (16260). ISSN 2045-2322
Reece, Emma and Doyle, Sean and Greally, Peter and Renwick, Julie and McClean, Siobhan (2018) Aspergillus fumigatus Inhibits Pseudomonas aeruginosa in Co-culture: Implications of a Mutually Antagonistic Relationship on Virulence and Inflammation in the CF Airway. Frontiers in Microbiology, 9 (1205). ISSN 1664-302X
Doyle, Sean and Jones, Gary W. and Dolan, Stephen K. (2018) Dysregulated gliotoxin biosynthesis attenuates the production of unrelated biosynthetic gene cluster-encoded metabolites in Aspergillus fumigatus. Fungal Biology, 122. pp. 214-221. ISSN 1878-6146
Saleh, Aliabbas A. and Jones, Gary W. and Tinley, Frances C. and Delaney, Stephen F. and Alabaddi, Sahar H. and Fenlon, Keith and Doyle, Sean and Owens, Rebecca A. (2018) Systems impact of zinc chelation by the epipolythiodioxopiperazine dithiol gliotoxin in Aspergillus fumigatus: a new direction in natural product functionality. Metallomics, 10. pp. 854-866. ISSN 1756-591X
Cullen, Louise and O'Connor, Andrew and McCormack, Sarah and Owens, Rebecca A. and Holt, Giles S. and Collins, Cassandra and Callaghan, Maire and Doyle, Sean and Smith, Darren and Schaffer, Kirsten and Fitzpatrick, David A. and McClean, Siobhan (2018) The involvement of the low-oxygen-activated locus of Burkholderia cenocepacia in adaptation during cystic fibrosis infection. Scientific Reports, 8 (1). p. 13386. ISSN 2045-2322
Waldron, Rose and McGowan, Jamie and Gordon, Natasha and McCarthy, Charley G.P. and Mitchell, E. Bruce and Doyle, Sean and Fitzpatrick, David A. (2017) Draft Genome Sequence of Dermatophagoides pteronyssinus, the European House Dust Mite. Genome Announcments, 5 (2). e00789-17. ISSN 2169-8287
Mulvihill, Eoin and Moloney, Nicola M. and Owens, Rebecca A. and Dolan, Stephen K. and Russell, Lauren and Doyle, Sean (2017) Functional Investigation of Iron-Responsive Microsomal Proteins, including MirC, in Aspergillus fumigatus. Frontiers in Microbiology, 8 (418). ISSN 1664-302X
Sipos, György and Prasanna, Arun N. and Walter, Mathias C. and Krizsán, Krisztina and Kiss, Brigitta and Hess, Jaqueline and Varga, Torda and Slot, Jason and Riley, Robert and Bóka, Bettina and Rigling, Daniel and Barry, Kerrie and Lee, Juna and Mihaltcheva, Sirma and LaButti, Kurt and Lipzen, Anna and Waldron, Rose and Moloney, Nicola M. and Sperisen, Christoph and Kredics, László and Vágvölgyi, Csaba and Patrignani, Andrea and Fitzpatrick, David A. and Nagy, István and Doyle, Sean and Anderson, James B. and Grigoriev, Igor V. and Münsterkötter, Martin and Nagy, László (2017) Genome expansion and lineage-specific genetic innovations in the forest pathogenic fungi Armillaria. Nature Ecology & Evolution, 1. pp. 1931-1941. ISSN 2397-334X
Delgado, Josué and Owens, Rebecca A. and Doyle, Sean and Núñez, Felix and Asensio, Miguel A. (2017) Quantitative proteomics reveals new insights into calcium-mediated resistance mechanisms in Aspergillus flavus against the antifungal protein PgAFP in cheese. Food Microbiology, 66. pp. 1-10. ISSN 1095-9998
Dolan, Stephen K. and Bock, Tobias and Hering, Vanessa and Owens, Rebecca A. and Jones, Gary W. and Blankenfeldt, Wulf and Doyle, Sean (2017) Structural, mechanistic and functional insight into gliotoxin bis-thiomethylation in Aspergillus fumigatus. Open Biology, 7 (2). ISSN 2046-2441
Alves de Castro, Patricia and dos Reis, Thaila Fernanda and Dolan, Stephen K. and Manfiolli, Adriana Oliveira and Brown, Neil Andrew and Jones, Gary W. and Doyle, Sean and Riaño‐Pachón, Diego M. and Squina, Fabio M. and Caldana, Camila and Singh, Ashutosh and Del Poeta, Maurizio and Hagiwara, Daisuke and Silva-Rocha, Rafael and Goldman, Gustavo H. (2016) The Aspergillus fumigatus SchASCH9 kinase modulates SakAHOG1 MAP kinase activity and it is essential for virulence. Molecular Microbiology, 102 (4). pp. 642-671. ISSN 1365-2958
Sheridan, Kevin J. and Lechner, Beatrix Elizabeth and O'Keeffe, Grainne and Keller, Markus A. and Werner, Ernst R. and Lindner, Herbert and Jones, Gary W. and Haas, Hubertus and Doyle, Sean (2016) Ergothioneine Biosynthesis and Functionality in the Opportunistic Fungal Pathogen, Aspergillus fumigatus. Scientific Reports, 6 (35306). ISSN 2045-2322
Amich, Jorge and Dümig, Michaela and O'Keeffe, Grainne and Binder, Jasmin and Doyle, Sean and Beilhack, Andreas and Krappmann, Sven (2016) Exploration of Sulfur Assimilation of Aspergillus fumigatus Reveals Biosynthesis of Sulfur-Containing Amino Acids as a Virulence Determinant. Infection and Immunity, 84 (4). pp. 917-929. ISSN 0019-9567
Delgado, Josué and Owens, Rebecca A. and Doyle, Sean and Asensio, Miguel A. and Núñez, Felix (2016) Increased chitin biosynthesis contributes to the resistance of Penicillium polonicum against the antifungal protein PgAFP. Applied Microbiology and Biotechnology, 100 (1). pp. 371-383. ISSN 1432-0614
McClean, Siobhan and Healy, Mark E. and Collins, Cassandra and Carberry, Stephen and O'Shaughnessy, Like and Dennehy, Ruth and Adams, Aine and Kennelly, Helen and Corbett, Jennifer and Carty, Fiona and Cahill, Laura A. and Callaghan, Maire and English, Karen and Mahon, Bernard P. and Doyle, Sean and Shinoy, Minu (2016) Linocin and OmpW Are Involved in Attachment of the Cystic Fibrosis-Associated Pathogen Burkholderia cepacia Complex to Lung Epithelial Cells and Protect Mice against Infection. Infection and Immunity, 84 (5). pp. 1424-1437. ISSN 0019-9567
Delgado, Josué and Owens, Rebecca A. and Doyle, Sean and Asensio, Miguel A. and Núñez, Felix (2016) Manuscript title: antifungal proteins from moulds: analytical tools and potential application to dry-ripened foods. Applied Microbiology and Biotechnology, 100 (16). pp. 6991-7000.
Manzanares-Miralles, Lara and Bayram, Ozgur and Sarikaya-Bayram, Ozlem and Smith, Elizabeth B. and Dolan, Stephen K. and Jones, Gary W. and Doyle, Sean (2016) Quantitative proteomics reveals the mechanism and consequence of gliotoxin-mediated dysregulation of the methionine cycle in Aspergillus niger. Journal of Proteomics, 131. pp. 149-162. ISSN 1874-3919
Smith, Elizabeth B. and Dolan, Stephen K. and Fitzpatrick, David A. and Doyle, Sean and Jones, Gary W. (2016) Towards understanding the gliotoxin detoxification mechanism: in vivo thiomethylation protects yeast from gliotoxin cytotoxicity. Microbial Cell, 3 (3). pp. 120-125. ISSN 2311-2638
Moloney, Nicola M. and Owens, Rebecca A. and Meleady, Paula and Henry, Michael and Dolan, Stephen K. and Mulvihill, Eoin and Clynes, Martin and Doyle, Sean (2016) The iron-responsive microsomal proteome of Aspergillus fumigatus. Journal of Proteomics, 136. pp. 99-111. ISSN 1874-3919
Fagan, Sheena and Owens, Rebecca A. and Ward, Patrick and Connolly, Cathal and Doyle, Sean and Murphy, Richard (2015) Biochemical Comparison of Commercial Selenium Yeast Preparations. Biological Trace Element Research, 166. pp. 245-259. ISSN 0163-4984
Sheridan, Kevin J. and Dolan, Stephen K. and Doyle, Sean (2015) Endogenous cross-talk of fungal metabolites. Frontiers in Microbiololgy, 5 (732). pp. 1-11. ISSN 1664-302X
Smith, Helen A. and Doyle, Sean and Murphy, Richard (2015) Filamentous fungi as a source of natural antioxidants. Food Chemistry, 185. pp. 389-397. ISSN 0308-8146
Owens, Rebecca A. and O'Keeffe, Grainne and Smith, Elizabeth B. and Dolan, Stephen K. and Hammel, Stephen and Sheridan, Kevin J. and Fitzpatrick, David A. and Keane, Thomas M. and Doyle, Sean (2015) Interplay between Gliotoxin Resistance, Secretion, and the Methyl/ Methionine Cycle in Aspergillus fumigatus. Eukaryotic Cell, 14 (9). pp. 941-957. ISSN 1535-9786
Medema, M.H. and Kottmann, R. and Yilmaz, P. and Cummings, M. and Biggins, J.B. and Blin, K. and de Bruijn, I. and Chooi, Y.H. and Claesen, J. and Coates, R.C. and Cruz-Morales, P. and Duddela, S. and Düsterhus, S. and Edwards, D.J. and Fewer, D.P. and Garg, N. and Geiger, C. and Gomez-Escribano, J.P. and Greule, A. and Hadjithomas, M. and Haines, A.S. and Helfrich, E.J. and Hillwig, M.L. and Ishida, K. and Jones, A.C. and Jones, C.S. and Jungmann, K. and Kegler, C. and Kim, H.U. and Kötter, P. and Krug, D. and Masschelein, J. and Melnik, A.V. and Mantovani, S.M. and Monroe, E.A. and Moore, M. and Moss, N. and Nützmann, H.W. and Pan, G. and Pati, A. and Petras, D. and Reen, F.J. and Rosconi, F. and Rui, Z. and Tian, Z. and Tobias, N.J. and Tsunematsu, Y. and Wiemann, P. and Wyckoff, E. and Yan, X. and Yim, G. and Yu, F. and Xie, Y. and Aigle, B. and Apel, A.K. and Balibar, C.J. and Balskus, E.P. and Barona-Gómez, F. and Bechthold, A. and Bode, H.B. and Borriss, R. and Brady, S.F. and Brakhage, Axel A. and Caffrey, P. and Cheng, Yo and Clardy, J. and Cox, R.J. and De Mot, R. and Donadio, S. and Donia, M.S. and van der Donk, W.A. and Dorrestein, P.C. and Doyle, Sean and Driessen, A.J. and Ehling-Schulz, M. and Entian, K.D. and Fischbach, M.A. and Gerwick, L. and Gerwick, W.H. and Gross, H. and Gust, B. and Hertweck, C. and Höfte, M. and Jensen, S.E. and Ju, J. and Katz, L. and Kaysser, L. and Klassen, J.L. and Keller, N.P. and Kormanec, J. and Kuipers, O.P. and Kuzuyama, T. and Kyrpides, N.C. and Kwon, H.J. and Lautru, S. and Lavigne, R. and Lee, C.Y. and Linquan, B. and Liu, X. and Liu, W. and Luzhetskyy, A. and Mahmud, T. and Mast, Y. and Méndez, C. and Metsä-Ketelä, M. and Micklefield, J. and Mitchell, D.A. and Moore, B.S. and Moreira, L.M. and Muller, R. and Neilan, B.A. and Nett, M. and Nielsen, J. and O'Gara, F. and Oikawa, H. and Osbourn, A. and Osburne, M.S. and Ostash, B. and Payne, S.M. and Pernodet, J.L. and Petricek, M. and Piel, J. and Ploux, O. and Raaijmakers, J.M. and Salas, J.A. and Schmitt, E.K. and Scott, B. and Seipke, R.F. and Shen, B. and Sherman, D.H. and Sivonen, K. and Smanski, M.J. and Sosio, M. and Stegmann, E. and Süssmuth, R.D. and Tahlan, K. and Thomas, C.M. and Tang, Y. and Truman, A.W. and Viaud, M. and Walton, J.D. and Walsh, C.T. and Weber, T. and van Wezel, G.P. and Wilkinson, B. and Willey, J.M. and Wohlleben, W. and Wright, G.D. and Ziemert, N. and Zhang, C. and Zotchev, S.B. and Breitling, R. and Takano, E. and Glöckner, F.O. (2015) Minimum Information about a Biosynthetic Gene cluster. Nature Chemical Biology, 11 (9). pp. 625-631. ISSN 1552-4469
Dolan, Stephen K. and O'Keefe, Grainne and Jones, Gary W. and Doyle, Sean (2015) Resistance is not futile: gliotoxin biosynthesis, functionality and utility. Trends in Microbiology, 23 (7). pp. 419-428. ISSN 0966-842X
Winkelstroter, Lizziane K. and Dolan, Stephen K. and Fernanda dos Reis, Thaila and Pedro Bom, Vinicius Leite and Alves de Castro, Patricia and Hagiwara, Daisuke and Alowni, Raneem and Jones, Gary W. and Doyle, Sean and Brown, Neil Andrew and Goldman, Gustavo H. (2015) Systematic Global Analysis of Genes Encoding Protein Phosphatases in Aspergillus fumigatus. G3 : Genes, Genomes, Genetics, 5. pp. 1525-1539. ISSN 2160-1836
O'Loughlin, Aran and McGee, Mark and Doyle, Sean and Earley, Bernadette (2014) Biomarker responses to weaning stress in beef calves. Research in Veterinary Science, 97 (2). pp. 457-463. ISSN 0034-5288
Johnson, Gemma and Ferrini, Arianna and Dolan, Stephen K. and Nolan, Tania and Agrawal, Samir and Doyle, Sean and Bustin, Stephen A. (2014) Biomarkers for invasive aspergillosis: the challenges continue. Biomarkers in Medicine, 8 (3). pp. 429-451. ISSN 1752-0363
Owens, Rebecca A. and Hammel, Stephen and Sheridan, Kevin J. and Jones, Gary W. and Doyle, Sean (2014) A Proteomic Approach to Investigating Gene Cluster Expression and Secondary Metabolite Functionality in Aspergillus fumigatus. PLoS ONE, 9 (9). e106942. ISSN 1932-6203
O’Keeffe, Grainne and Hammel, Stephen and Owens, Rebecca A. and Keane, Thomas M. and Fitzpatrick, David A. and Jones, Gary W. and Doyle, Sean (2014) RNA-seq reveals the pan-transcriptomic impact of attenuating the gliotoxin self-protection mechanism in Aspergillus fumigatus. BMC Genomics, 15 (894). pp. 1-26. ISSN 1471-2164
Dolan, Stephen K. and Owens, Rebecca A. and O'Keefe, Grainne and Hammel, Stephen and Fitzpatrick, David A. and Jones, Gary W. and Doyle, Sean (2014) Regulation of Nonribosomal Peptide Synthesis: bis-Thiomethylation Attenuates Gliotoxin Biosynthesis in Aspergillus fumigatus. Chemistry and Biology, 21 (8). pp. 999-2012. ISSN 1074-5521
Jones, Gary W. and Doyle, Sean and Fitzpatrick, David A. (2014) The evolutionary history of the genes involved in the biosynthesis of the antioxidant ergothioneine. Gene, 549 (1). pp. 161-170. ISSN 0378-1119
Culleton, Bridget A. and Lall, Patrick and Kinsella, Gemma K. and Doyle, Sean and McCaffrey, John G. and Fitzpatrick, David A. and Burnell, Ann (2014) A role for the Parkinson’s disease protein DJ-1 as a chaperone and antioxidant in the anhydrobiotic nematode Panagrolaimus superbus. Cell Stress & Chaperones, 20 (1). pp. 121-137. ISSN 1355-8145
O'Keeffe, Grainne and Jöchl, Christoph and Kavanagh, Kevin and Doyle, Sean (2013) Extensive proteomic remodeling is induced by eukaryotic translation elongation factor 1Bc deletion in Aspergillus fumigatus. Protein Science, 22 (11). pp. 1612-1622. ISSN 0961-8368
Collins, Cassandra and Keane, Thomas M. and Turner, Daniel J. and O'Keefe, Grainne and Fitzpatrick, David A. and Doyle, Sean (2013) Genomic and Proteomic Dissection of the Ubiquitous Plant Pathogen, Armillaria mellea: Toward a New Infection Model System. Journal of Proteome Research, 12. pp. 2552-2570. ISSN 1535-3893
Shinoy, Minu and Dennehy, Ruth and Coleman, Elaine and Carberry, Stephen and Schaffer, Kirsten and Callaghan, Maire and Doyle, Sean and McClean, Siobhan (2013) Immunoproteomic Analysis of Proteins Expressed by Two Related Pathogens, Burkholderia multivorans and Burkholderia cenocepacia, during Human Infection. PLoS ONE, 8 (11). ISSN 1932-6203
Keady, S.M. and Kenny, D.A. and Ohlendieck, Kay and Doyle, Sean and Keane, M.G. and Waters, S.M. (2013) Proteomic profiling of bovine M. longissimus lumborum from Crossbred Aberdeen Angus and Belgian Blue sired steers varying in genetic merit for carcass weight. Journal of Animal Science, 91 (2). pp. 654-665. ISSN 0021-8812
O’Loughlin, Aran and Lynn, David J. and McGee, Mark and Doyle, Sean and McCabe, Matthew and Earley, Bernadette (2012) Transcriptomic analysis of the stress response to weaning at housing in bovine leukocytes using RNA-seq technology. BMC Genomics, 13 (250). pp. 1-18. ISSN 1471-2164
O'Hanlon, Karen and Gallagher, Lorna and Schrettl, Markus and Jöchl, Christoph and Kavanagh, Kevin and Larsen, Thomas O. and Doyle, Sean (2012) Nonribosomal Peptide Synthetase Genes pesL and pes1 Are Essential for Fumigaclavine C Production in Aspergillus fumigatus. Applied and Environmental Microbiology , 78 (10). pp. 3166-3176. ISSN 0099-2240
Marquesa, Marco P.C. and Walshe, Kieran and Doyle, Sean and Fernandesa, Pedro and de Carvalhoa, Carla C.C.R. (2012) Anchoring high-throughput screening methods to scale-up bioproduction of siderophores. Process Biochemistry, 47 (3). pp. 416-421. ISSN 1359-5113
Lynch, Eilish M. and McGee, Mark and Doyle, Sean and Earley, Bernadette (2012) Effect of pre-weaning concentrate supplementation on peripheral distribution of leukocytes, functional activity of neutrophils, acute phase protein and behavioural responses of abruptly weaned and housed beef calves. BMC Veterinary Research, 8 (1). ISSN 1746-6148
Carberry, Stephen and Molloy, Emer and Hammel, Stephen and O'Keefe, Grainne and Jones, Gary W. and Kavanagh, Kevin and Doyle, Sean (2012) Gliotoxin effects on fungal growth: Mechanisms and exploitation. Fungal Genetics and Biology, 49 (4). pp. 302-312. ISSN 1087-1845
O'Hanlon, Karen and Margison, Geoffrey P. and Hatch, Amy and Fitzpatrick, David A. and Owens, Rebecca A. and Doyle, Sean and Jones, Gary W. (2012) Molecular characterization of an adaptive response to alkylating agents in the opportunistic pathogen Aspergillus fumigatus. Nucleic Acids Research, 40 (16). pp. 7806-7820. ISSN 0305-1048
Gallagher, Lorna and Owens, Rebecca A. and Dolan, Stephen K. and O'Keefe, Grainne and Schrettl, Markus and Kavanagh, Kevin and Jones, Gary W. and Doyle, Sean (2012) The Aspergillus fumigatus Protein GliK Protects against Oxidative Stress and Is Essential for Gliotoxin Biosynthesis. Eukaryotic Cell, 11 (10). pp. 1226-1238. ISSN 1535-9778
Doyle, Sean (2011) The Detection of Parvoviruses. Methods in Molecular Biology, 665. pp. 213-231. ISSN 1064-3745
Lynch, E.M. and McGee, M. and Doyle, Sean and Earley, B. (2011) Effect of post-weaning management practices on physiological and immunological responses of weaned beef calves. Irish Journal of Agricultural and Food Research, 50 (2). pp. 161-174. ISSN 07916833
O'Loughlin, Aran and McGee, Mark and Waters, Sinead M. and Doyle, Sean and Earley, Bernadette (2011) Examination of the bovine leukocyte environment using immunogenetic biomarkers to assess immunocompetence following exposure to weaning stress. BMC Veterinary Research, 7 (45). ISSN 1746-6148
Doyle, Sean (2011) Fungal proteomics: from identification to function. FEMS Microbiology Letters, 321 (1). pp. 1-9. ISSN 0378-1097
Doyle, Sean (2011) Fungal proteomics: from identitcation to function. Microbiology Letters, 321. pp. 1-9.
O'Shaughnessy, Luke and Carr, Michael and Crowley, Brendan and Carberry, Stephen and Doyle, Sean (2011) Recombinant expression and immunological characterisation of proteins derived from human metapneumovirus. Journal of Clinical Virology, 52 (3). pp. 236-243. ISSN 1386-6532
Davis, Carol and Gordon, Natasha and Murphy, Sinead and Singh, Ishwar and Kavanagh, Kevin and Carberry, Stephen and Doyle, Sean (2011) Single-pot derivatisation strategy for enhanced gliotoxin detection by HPLC and MALDI-ToF mass spectrometry. Analytical and Bioanalytical Chemistry, 401 (8). pp. 2519-2529. ISSN 1618-2642
O'Hanlon, Karen and Cairns, Timothy and Stack, Deirdre and Schrettl, Markus and Bignell, Elaine and Kavanagh, Kevin and Miggin, Sinead and O'Keeffe, Grainne and Larsen, Thomas and Doyle, Sean (2011) Targeted Disruption of Nonribosomal Peptide Synthetase pes3 Augments the Virulence of Aspergillus fumigatus. Infection and Immunity, 79 (10). pp. 3978-3992. ISSN 0019-9567
Davis, Carol and Carberry, Stephen and Schrettl, Markus and Singh, Ishwar and Stephens, John C. and Barry, Sarah M. and Kavanagh, Kevin and Challis, Gregory L. and Brougham, Dermot and Doyle, Sean (2011) The Role of Glutathione S-Transferase GliG in Gliotoxin Biosynthesis in Aspergillus fumigatus. Chemistry and Biology, 18. pp. 542-552. ISSN 1074-5521
Lynch, Eilish M. and Earley, Bernadette and McGee, Mark and Doyle, Sean (2010) Characterisation of physiological and immunological responses in beef cows to abrupt weaning and subsequent housing. BMC Veterinary Research, 6 (37). pp. 1-8. ISSN 1746-6148
Lynch, E.M. and Earley, B. and McGee, M. and Doyle, Sean (2010) Effect of abrupt weaning at housing on leukocyte distribution, functional activity of neutrophils, and acute phase protein response of beef calves. BMC Veterinary Research, 6 (39). pp. 1-9. ISSN 1746-6148
Schrettl, Markus and Carberry, Stephen and Kavanagh, Kevin and Haas, Hubertus and Jones, Gary W. and O'Brien, Jennifer and Nolan, Aine and Stephens, John C. and Fenelon, Orla and Doyle, Sean (2010) Self-Protection against Gliotoxin—A Component of the Gliotoxin Biosynthetic Cluster, GliT, Completely Protects Aspergillus fumigatus Against Exogenous Gliotoxin. PLOS Pathogens, 6 (6). ISSN 1553-7366
Gaffney, Mark and Doyle, Sean and Murphy, Richard (2009) Optimization of Xylanase Production by Thermomyces Ianuginosus in Solid State Fermentation. Bioscience, Biotechnology, and Biochemistry, 74 (12). pp. 2640-2644. ISSN 0916-8451
Gaffney, Mark and Carberry, Stephen and Doyle, Sean and Murphy, Richard (2009) Purification and characterisation of a xylanase from Thermomyces lanuginosus and its functional expression by Pichia pastoris. Enzyme and Microbial Technology, 45 (5). pp. 348-354. ISSN 0141-0229
Stack, Deirdre and Frizzell, Aisling and Tomkins, Karen and Doyle, Sean (2009) Solid Phase 4′-Phosphopantetheinylation: Fungal Thiolation Domains are Targets for Chemoenzymatic Modification. Bioconjugate Chemistry, 20 (8). pp. 1514-1522. ISSN 1043-1802
Stack, Deirdre and Neville, Claire and Doyle, Sean (2007) Nonribosomal peptide synthesis in Aspergillus fumigatus and other fungi. Microbiology, 153 (5). pp. 1297-1306. ISSN 1465-2080
Corcoran, A. and Kerr, S. and Elliott, G. and Koppelman, M. and Doyle, Sean (2007) Improved detection of acute parvovirus B19 infection by immunoglobulin M EIA in combination with a novel antigen EIA. Vox Sanguinis, 96 (3). pp. 216-222. ISSN 0042-9007
Vickers, Imelda and Reeves, Emer P. and Kavanagh, Kevin and Doyle, Sean (2007) Isolation, activity and immunological characterisation of a secreted aspartic protease, CtsD, from Aspergillus fumigatus. Protein Expression and Purification, 53 (1). pp. 216-224. ISSN 1046-5928
Carberry, Stephen and Doyle, Sean (2007) Proteomic studies in biomedically and industrially relevant fungi. Cytotechnology, 53 (1-3). pp. 95-100. ISSN 0920-9069
Reeves, Emer P. and Reiber, Kathrin and Neville, Claire and Scheibner, Olaf and Kavanagh, Kevin and Doyle, Sean (2006) A nonribosomal peptide synthetase (Pes1) confers protection against oxidative stress in Aspergillus fumigatus. The FEBS Journal, 273 (13). pp. 3038-3053. ISSN 1742-464X
Carberry, Stephen and Neville, Claire M. and Kavanagh, Kevin and Doyle, Sean (2006) Analysis of major intracellular proteins of Aspergillus fumigatus by MALDI mass spectrometry: Identification and characterisation of an elongation factor 1B protein with glutathione transferase activity. Biochemical and Biophysical Research Communications, 341 (4). pp. 1096-1104. ISSN 0006-291X
Corcoran, A. and Crowley, B. and Dewhurst, C. and Pizer, B.L. and Doyle, Sean (2006) Establishment of Functional B Cell Memory Against Parvovirus B19 Capsid Proteins May be Associated With Resolution of Persistent Infection. Journal of Medical Virology, 78 (1). pp. 125-128. ISSN 0146-6615
Corcoran, A. and Doyle, Sean (2006) Human Parvovirus B19: Molecular Virology, Clinical Features, Prevalence, Diagnosis and Control. In: Congenital and Other Related Infectious Diseases of the Newborn. Perspectives in Medical Virology (13). Elsevier, pp. 173-209. ISBN 9780444520746
Doyle, Sean and Corcoran, Amanda (2006) The Immune Response to Parvovirus B19 Exposure in previously Seronegative and Seropositive Individuals. Journal of Infectious Diseases, 194 (2). pp. 154-158. ISSN 0022-1899
Reiber, Kathrin and Reeves, Emer P. and Neville, Claire M. and Winkler, Robert and Gebhardt, Peter and Kavanagh, Kevin and Doyle, Sean (2005) The expression of selected non-ribosomal peptide synthetases in Aspergillus fumigatus is controlled by the availability of free iron. FEMS Microbiology Letters, 248 (1). pp. 83-91. ISSN 0378-1097
Neville, Claire and Murphy, Alan and Kavanagh, Kevin and Doyle, Sean (2005) A 4'-Phosphopantetheinyl Transferase Mediates Non-Ribosomal Peptide Synthetase Activation in Aspergillus fumigatus. ChemBioChem, 6 (4). pp. 679-685.
Burns, Claire and Geraghty, Rachel and Neville, Claire and Murphy, Alan and Kavanagh, Kevin and Doyle, Sean (2005) Identification, cloning, and functional expression of three glutathione transferase genes from Aspergillus fumigatus. Fungal Genetics and Biology, 42 (4). pp. 319-327. ISSN 1087-1845
Waters, Sinead M. and Doyle, Sean and Murphy, Richard A. and Power, Ronan F.G. (2005) Development of solution phase hybridisation PCR-ELISA for the detection and quantification of Enterococcus faecalis and Pediococcus pentosaceus in Nurmi-type cultures. Journal of Microbiological Methods, 63 (3). pp. 264-275. ISSN 0167-7012
Corcoran, Amanda and Doyle, Sean and Allain, J.P. and Candotti, D. and Parsyan, A. (2005) Letter to the Editor Evidence of Serological Cross-Reactivity between Genotype 1 and Genotype 3 Erythrovirus Infections. Journal of Virology, 79 (8). pp. 5238-5239.
Doyle, Sean and Corcoran, Amanda (2004) Advances in the biology, diagnosis and host-pathogen interactions of parvovirus B19. Journal of Medical Microbiology, 53. pp. 1-17.
Corcoran, Amanda and Mahon, Bernard P. and Doyle, Sean (2004) B Cell Memory Is Directed toward Conformational Epitopes of Parvovirus B19 Capsid Proteins and the Unique Region of VP1. Journal of Infectious Diseases, 189 (10). pp. 1873-1880. ISSN 0022-1899
Collins, Peter R. and Stack, Colin M. and O'Neill, Sandra M. and Doyle, Sean and Ryan, Thecla and Brennan, Gerard and Mousley, Angela and Stewart, Michael and Maule, Aaron G. and Dalton, John P. and Donnelly, Sheila (2004) Cathepsin L1, the Major Protease Involved in Liver Fluke (Fasciola hepatica) Virulence. Journal of Biological Chemistry, 279 (17). pp. 17038-17046. ISSN 0021-9258
Reeves, Emer P. and Messina, C.G.M. and Doyle, Sean and Kavanagh, Kevin (2004) Correlation between gliotoxin production and virulence of Aspergillus fumigatus in Galleria mellonella. Mycopathologia, 158 (1). pp. 73-79. ISSN 0301-486X
Doyle, Sean and Fox, M. and Gray, G. and Kavanagh, Kevin (2004) Detection of Aspergillus fumigatus mycotoxins: immunogen synthesis and immunoassay development. Journal of Microbiological Methods, 56 (2). pp. 221-230. ISSN 0167-7012
McCarthy, Elaine and Stack, Colin and Donnelly, Sheila M. and Doyle, Sean and Mann, Victoria H. and Brindley, Paul J. and Stewart, Michael and Day, Tim A. and Maule, Aaron G. and Dalton, John P. (2004) Leucine aminopeptidase of the human blood flukes, Schistosoma mansoni and Schistosoma japonicum. International Journal of Parasitology, 34 (6). pp. 703-714. ISSN 0020-7519
O'Keeffe, Joseph and Doyle, Sean and Kavanagh, Kevin (2003) Exposure of the yeast Candida albicans to the anti-neoplastic agent adriamycin increases the tolerance to amphotericin B. Journal of Pharmacy and Pharmacology, 55 (12). pp. 1629-1633.
Mahon, Bernard P. and Corcoran, Amanda and McParland, Peter and Davoren, Anne and Doyle, Sean (2003) Ex Vivo Cytokine responses against Parvovirus B19 Antigens in previously infected pregnant women. Journal of Medial Virology, 70 (3). pp. 475-480. ISSN 0146-6615
Dalton, John P. and O'Neill, Sandra M. and Stack, Colin M. and Collins, Peter R. and Walshe, Alan and Sekiya, Mary and Doyle, Sean and Mulcahy, Grace and Hoyle, Deborah and Khaznadji, Eric and Moire, Nathalie and Brennan, Gerard and Mousley, Angela and Kreshchenko, Natalia and Maule, Aaron G. and Donnelly, Sheila M. (2003) Fasciola hepatica cathepsin L-like proteases: biology, function, and potential in the development of first generation liver fluke vaccines. International Journal for Parasitology, 33 (11). pp. 1173-1181. ISSN 0020-7519
Deegan, Orla and Walshe, Kieran and Kavanagh, Kevin and Doyle, Sean (2003) Quantitative detection of C-reactive protein using phosphocholine-labelled enzyme or microspheres. Analytical Biochemistry, 312 (2). pp. 175-181. ISSN 0003-2697
Doyle, Sean and Daly, Paul (2003) The development of a competitive PCR-ELISA for the detection of equine herpesvirus-1. Journal of Virological Methods, 107 (2). pp. 237-244. ISSN 0166-0934
Doyle, Sean and Mahon, Bernard P. and Corcoran, A. and Daly, P. (2002) High-Sensitivity PCR Detection of Parvovirus B19 Plasma. Journal of Clinical Microbiology, 40 (6). pp. 1958-1962.
Raab, Ulla and Beckenlehner, Karin and Lowin, Tosten and Niller, Hans-Helmut and Doyle, Sean and Modrow, Susanne (2002) NS1 Protein of Parvovirus B19 Interacts Directly with DNA Sequences of the p6 Promoter and with the Cellular Transcription Factors Sp1/Sp3. Virology, 293 (1). pp. 86-93. ISSN 0042-6822
Doyle, Sean and Daly, Paul and Collier, T. (2002) PCR-ELISA detection of Escherichia coli in milk. Letters in Applied Microbiology, 34 (3). pp. 222-226. ISSN 0266-8254
Mahon, Bernard P. and Doyle, Sean and Kavanagh, Kevin and Corcoran, Amanda and Ennis, O. (2001) Baculovirus expression of parvovirus B19 (B19V) NS1: utility in confirming recent infection. Journal of Clinical Virology, 22 (1). pp. 55-60. ISSN 1386-6532
Doyle, Sean (2001) Paravovirus B19 infection - an underestimated problem. In: The Irish Scientist. Samton Limited, p. 139. ISBN 1898706239
Doyle, Sean and Kerr, S. and O'Keeffe, Grainne and O'Carroll, D. and Daly, P. and Kilty, C. (2000) Detection of parvovirus B19 IgM by antibody capture enzyme immunoassay: receiver operating characteristic analysis. Journal of Virological Methods, 90 (2). pp. 143-1522. ISSN 0166-0934
Cotter, Gary and Doyle, Sean and Kavanagh, Kevin (2000) Development of an insect model for the in vivo pathogenicity testing of yeasts. FEMS Immunology and Medical Microbiology, 27 (2). pp. 163-169. ISSN 0928-8244
Corcoran, Amanda and Doyle, Sean and Waldron, David and Nicholson, Alfred and Mahon, Bernard P. (2000) Impaired Gamma Interferon Responses against Parvovirus B19 by Recently Infected Children. Journal of Virology, 74 (21). pp. 9903-9910. ISSN 0022-538X
Flendring, Leonard M. and Chamuleau, Robert A.F.M. and Maas, Martinus A.W. and Daalhuisen, Joost and Hasset, Brian and Kilty, Cormac G. and Doyle, Sean and Ladiges, Nita C.J.J. and Jörning, George G.A. and la Soe, John W. and Sommeijer, Dirkje and te Velde, Anje A. (1999) Evaluation of a novel bioartificial liver in rats with complete liver ischemia: treatment efficacy and species-specific alpha-GST detection to monitor hepatocyte viability. Journal of Hepatology, 30 (2). pp. 311-321. ISSN 0168-8278
Kerr, S. and O'Keeffe, Grainne and Kilty, C. and Doyle, Sean (1999) Undenatured parvovirus B19 antigens are essential for the accurate detection of parvovirus B19 IgG. Journal of Medical Virology, 57 (2). pp. 179-185. ISSN 0146-6615
Eckersall, P.D. and Duthie, S. and Safi, S. and Moffatt, D. and Horadagoda, N.U. and Doyle, Sean and Parton, R. and Bennett, D. and Fitzpatrick, J.L. (1999) An automated biochemical assay for haptoglobin: prevention of interference from albumin. Comparative Haematology International, 9 (3). pp. 117-124. ISSN 0938-7714
Kilty, Cormac and Doyle, Sean and Hassett, Brian and Manning, Fiona (1998) Glutathione S-transferases as biomarkers of organ damage: applications of rodent and canine GST enzyme immunoassays. Chemico-Biological Interactions, 111. pp. 123-135. ISSN 0009-2797
Clarke, H. and Egan, DA and Heffernan, M. and Doyle, Sean and Byrne, C. and Kilty, C. and Ryan, MP (1997) α-glutathione s-transferase (α-GST) release, an early indicator of carbon tetrachloride hepatotoxicity in the rat. Human & Experimental Toxicology, 16 (3). pp. 154-157. ISSN 0960-3271
McCormack, Christine C. and Hobson, Audrey H. and Doyle, Sean and Jackson, John and Kilty, Cormac and Whitehead, Alexander S. (1996) Generation of soluble recombinant human acute phase serum amyloid A2 protein and its use in the development of an A-SAA specific ELISA. Journal of Immunological Methods, 198 (1). pp. 101-110. ISSN 0022-1759
Rees, Gareth W. and Trull, Andrew K. and Doyle, Sean (1995) Evaluation of an Enzyme-Immunometric Assay for Serum α-Glutathione S-Transferase. Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 32 (6). pp. 575-583. ISSN 1758-1001
Doyle, Sean and Schininà, M.E. and Bossa, F. and Doonan, S. (1990) The amino acid sequence of cytosolic aspartate aminotransferase from human liver. Biochemical Journal, 270 (3). pp. 651-657. ISSN 0264-6021
