Article

Gargan, Stephen, Dowling, Paul, Zweyer, Margit, Reimann, Jens, Henry, Michael, Meleady, Paula, Swandulla, Dieter and Ohlendieck, Kay (2021) Mass Spectrometric Profiling of Extraocular Muscle and Proteomic Adaptations in the mdx-4cv Model of Duchenne Muscular Dystrophy. Life, 11 (7). p. 595. ISSN 2075-1729

Dowling, Paul, Gargan, Stephen, Zweyer, Margit, Sabir, Hemmen, Henry, Michael, Meleady, Paula, Swandulla, Dieter and Ohlendieck, Kay (2021) Proteomic profiling of the interface between the stomach wall and the pancreas in dystrophinopathy. European Journal of Translational Myology, 31 (1). ISSN 2037-7452

Dowling, Paul, Zweyer, Margit, Raucamp, Maren, Henry, Michael, Meleady, Paula, Swandulla, Dieter and Ohlendieck, Kay (2020) Dataset on the mass spectrometry-based proteomic profiling of the kidney from wild type and the dystrophic mdx-4cv mouse model of X-linked muscular dystrophy. Data in Brief, 28 (105067). pp. 1-9. ISSN 2352-3409

Gargan, Stephen, Dowling, Paul, Zweyer, Margit, Swandulla, Dieter and Ohlendieck, Kay (2020) Identification of marker proteins of muscular dystrophy in the urine proteome from the mdx-4cv model of dystrophinopathy. Molecular Omics, 16 (3). pp. 268-278. ISSN 2515-4184

Dowling, Paul, Gargan, Stephen, Zweyer, Margit, Henry, Michael, Meleady, Paula, Swandulla, Dieter and Ohlendieck, Kay (2020) Proteome-wide Changes in the mdx-4cv Spleen due to Pathophysiological Cross Talk with Dystrophin-Deficient Skeletal Muscle. iScience, 23 (101500). ISSN 2589-0042

Dowling, Paul, Zweyer, Margit, Raucamp, Maren, Henry, Michael, Meleady, Paula, Swandulla, Dieter and Ohlendieck, Kay (2020) Proteomic and cell biological profiling of the renal phenotype of the mdx-4cv mouse model of Duchenne muscular dystrophy. European Journal of Cell Biology, 99 (151059). ISSN 0171-9335

Dowling, Paul, Gargan, Stephen, Zweyer, Margit, Henry, Michael, Meleady, Paula, Swandulla, Dieter and Ohlendieck, Kay (2020) Protocol for the Bottom-Up Proteomic Analysis of Mouse Spleen. STAR Protocols, 1 (100196). ISSN 2666-1667

Dowling, Paul, Zweyer, Margit, Swandulla, Dieter and Ohlendieck, Kay (2019) Characterization of Contractile Proteins from Skeletal Muscle Using Gel-Based Top-Down Proteomics. Proteomes, 7 (2). ISSN 2227-7382

Dowling, Paul, Murphy, Sandra, Zweyer, Margit, Raucamp, Maren, Swandulla, Dieter and Ohlendieck, Kay (2019) Emerging proteomic biomarkers of X-linked muscular dystrophy. Expert Review of Molecular Diagnostics, 19 (8). pp. 739-755. ISSN 1473-7159

Murphy, Sandra, Zweyer, Margit, Raucamp, Maren, Henry, Michael, Meleady, Paula, Swandulla, Dieter and Ohlendieck, Kay (2019) Proteomic profiling of the mouse diaphragm and refined mass spectrometric analysis of the dystrophic phenotype. Journal of Muscle Research and Cell Motility, 40. pp. 9-28. ISSN 0142-4319

Murphy, Sandra, Zweyer, Margit, Mundegar, Rustam R., Swandulla, Dieter and Ohlendieck, Kay (2018) Comparative gel-based proteomic analysis of chemically crosslinked complexes in dystrophic skeletal muscle. Electrophoresis, 39. pp. 1735-1744. ISSN 0173-0835

Murphy, Sandra, Zweyer, Margit, Mundegar, Rustam R., Swandulla, Dieter and Ohlendieck, Kay (2018) Dataset on the comparative proteomic profiling of mouse saliva and serum from wild type versus the dystrophic mdx-4cv mouse model of dystrophinopathy. Data in Brief, 21. pp. 1236-1245. ISSN 2352-3409

Murphy, Sandra, Zweyer, Margit, Henry, Michael, Meleady, Paula, Mundegar, Rustam R, Swandulla, Dieter and Ohlendieck, Kay (2018) Proteomic analysis of the sarcolemma-enriched fraction from dystrophic mdx-4cv skeletal muscle. Journal of Proteomics, 191. pp. 212-227. ISSN 1874-3919

Murphy, Sandra, Zweyer, Margit, Mundegar, Rustam R., Swandulla, Dieter and Ohlendieck, Kay (2018) Proteomic identification of elevated saliva kallikrein levels in the mdx-4cv mouse model of Duchenne muscular dystrophy. Biochemistry and Biophysics Reports, 18 (100541). ISSN 2405-5808

Murphy, Sandra and Ohlendieck, Kay (2018) Proteomic profiling of large myofibrillar proteins from dried and long-term stored polyacrylamide gels. Analytical Biochemistry, 543. pp. 8-11. ISSN 0003-2697

Murphy, Sandra, Zweyer, Margit, Henry, Michael, Meleady, Paula, Mundegar, Rustam R., Swandulla, Dieter and Ohlendieck, Kay (2018) Proteomic profiling of liver tissue from the mdx-4cv mouse model of Duchenne muscular dystrophy. Clinical Proteomics, 15 (34). ISSN 1559-0275

Murphy, Sandra, Zweyer, Margit, Henry, Michael, Meleady, Paula, Mundegar, Rustam R., Swandulla, Dieter and Ohlendieck, Kay (2018) Subproteomic profiling of sarcolemma from dystrophic mdx-4cv skeletal muscle. Data in Brief, 17. pp. 980-993. ISSN 2352-3409

Murphy, Sandra and Ohlendieck, Kay (2017) Mass spectrometric identification of dystrophin, the protein product of the Duchenne muscular dystrophy gene, in distinct muscle surface membranes. International Journal of Molecular Medicine, 40 (4). pp. 1078-1088. ISSN 1107-3756

Murphy, Sandra, Brinkmeier, Heinrich, Krautwald, Mirjam, Henry, Michael, Meleady, Paula and Ohlendieck, Kay (2017) Proteomic profiling of the dystrophin complex and membrane fraction from dystrophic mdx muscle reveals decreases in the cytolinker desmoglein and increases in the extracellular matrix stabilizers biglycan and fibronectin. Journal of Muscle Research and Cell Motility, 38 (2). pp. 251-368. ISSN 0142-4319

Ohlendieck, Kay and Swandulla, Dieter (2017) Molekulare Pathogenese der Fibrose bei Muskeldystrophie vom Typ Duchenne - Molecular pathogenesis of Duchenne muscular dystrophy-related fibrosis. Der Pathologe, 38 (1). pp. 21-29. ISSN 0172-8113

Murphy, Sandra, Dowling, Paul, Zweyer, Margit, Henry, Michael, Meleady, Paula, Mundegar, Rustam R., Swandulla, Dieter and Ohlendieck, Kay (2017) Proteomic profiling of mdx-4cv serum reveals highly elevated levels of the inflammation-induced plasma marker haptoglobin in muscular dystrophy. International Journal of Molecular Medicine, 39 (6). pp. 1357-1370. ISSN 1791-244X

Carberry, Steven, Zweyer, Margit, Swandulla, Dieter and Ohlendieck, Kay (2014) Comparative proteomic analysis of the contractile-protein-depleted fraction from normal versus dystrophic skeletal muscle. Analytical Biochemistry, 446. pp. 108-115. ISSN 0003-2697

Holland, Ashling, Schmitt-John, Thomas, Dowling, Paul, Meleady, Paula, Henry, Michael, Clynes, Martin and Ohlendieck, Kay (2014) Intricate effects of primary motor neuronopathy on contractile proteins and metabolic muscle enzymes as revealed by label-free mass spectrometry. Bioscience Reports, 34 (4). pp. 331-343. ISSN 1573-4935

Dowling, Paul, Holland, Ashling and Ohlendieck, Kay (2014) Mass Spectrometry-Based Identification of Muscle-Associated and Muscle-Derived Proteomic Biomarkers of Dystrophinopathies. Journal of Neuromuscular Diseases, 1 (1). pp. 15-40. ISSN 2214-3599

Holland, Ashling, Dowling, Paul and Ohlendieck, Kay (2014) New pathobiochemical insights into dystrophinopathy from the proteomics of senescent mdx mouse muscle. Frontiers in Aging Neuroscience, 6 (109). pp. 1-5. ISSN 1663-4365

Jockusch, Harald, Holland, Ashling, Staunton, Lisa, Schmitt-John, Thomas, Heimann, Peter, Dowling, Paul and Ohlendieck, Kay (2014) Pathoproteomics of testicular tissue deficient in the GARP component VPS54: The wobbler mouse model of globozoospermia. Proteomics, 14 (7-8). pp. 839-852. ISSN 1615-9853

Carberry, Steven, Zweyer, Margit, Swandulla, Dieter and Ohlendieck, Kay (2013) Application of Fluorescence Two-Dimensional Difference In-Gel Electrophoresis as a Proteomic Biomarker Discovery Tool in Muscular Dystrophy Research. Biology, 2. pp. 1438-1464. ISSN 2079-7737

Carberry, Steven, Brinkmeier, Heinrich, Zhang, Yaxin, Winkler, Claudia K. and Ohlendieck, Kay (2013) Comparative proteomic profiling of soleus, extensor digitorum longus, flexor digitorum brevis and interosseus muscles from the mdx mouse model of Duchenne muscular dystrophy. International Journal of Molecular Medicine, 32 (374). pp. 544-556. ISSN 1107-3756

Keady, S.M., Kenny, D.A., Ohlendieck, Kay, Doyle, Sean, Keane, M.G. and Waters, S.M. (2013) Proteomic profiling of bovine M. longissimus lumborum from Crossbred Aberdeen Angus and Belgian Blue sired steers varying in genetic merit for carcass weight. Journal of Animal Science, 91 (2). pp. 654-665. ISSN 0021-8812

Holland, Ashling, Dowling, Paul, Zweyer, Margit, Swandulla, Dieter, Henry, Michael, Clynes, Martin and Ohlendieck, Kay (2013) Proteomic profiling of cardiomyopathic tissue from the aged mdx model of Duchenne muscular dystrophy reveals a drastic decrease in laminin, nidogen and annexin. Proteomics, 13 (15). pp. 2312-2323. ISSN 1615-9853

Staunton, Lisa, Zweyer, Margit, Swandulla, Dieter and Ohlendieck, Kay (2012) Mass spectrometry-based proteomic analysis of middle-aged vs. aged vastus lateralis reveals increased levels of carbonic anhydrase isoform 3 in senescent human skeletal muscle. International Journal of Molecular Medicine, 30 (4). pp. 723-733. ISSN 1107-3756

Carberry, Steven, Zweyer, Margit, Swandulla, Dieter and Ohlendieck, Kay (2012) Profiling of Age-Related Changes in the Tibialis Anterior Muscle Proteome of the mdx Mouse Model of Dystrophinopathy. Journal of Biomedicine and Biotechnology, 2012 (691641). ISSN 1110-7243

Carberry, Steven, Zweyer, Margit, Swandulla, Dieter and Ohlendieck, Kay (2012) Proteomics reveals drastic increase of extracellular matrix proteins collagen and dermatopontin in the aged mdx diaphragm model of Duchenne muscular dystrophy. International Journal of Molecular Medicine, 30 (2). pp. 229-234. ISSN 1107-3756

Gannon, Jay and Ohlendieck, Kay (2012) Subproteomic analysis of basic proteins in aged skeletal muscle following offgel pre-fractionation. Molecular Medicine Reports, 5 (4). pp. 993-1000. ISSN 1791-2997

Mullen, Edel and Ohlendieck, Kay (2011) Proteomic analysis of the mitochondria-enriched fraction from diabetic rat skeletal muscle. Journal of Integrated Omics, 1 (1). pp. 108-114. ISSN 2182-0287

Ohlendieck, Kay (2011) Skeletal muscle proteomics: current approaches, technical challenges and emerging techniques. Skeletal Muscle, 1 (6). pp. 1-15.

Staunton, Lisa, Jockusch, Harald, Wiegand, Christiane, Albrecht, Timo and Ohlendieck, Kay (2011) Identification of secondary effects of hyperexcitability by proteomic profiling of myotonic mouse muscle. Molecular BioSystems, 8. pp. 2480-2489. ISSN 1742-206X

Lewis, Caroline and Ohlendieck, Kay (2011) Mass spectrometric identification of dystrophin isoform Dp427 by on-membrane digestion of sarcolemma from skeletal muscle. Analytical Biochemistry, 404 (2). pp. 197-203. ISSN 0003-2697

Staunton, Lisa, O’Connell, Kathleen and Ohlendieck, Kay (2011) Proteomic Profiling of Mitochondrial Enzymes during Skeletal Muscle Aging. Journal of Aging Research (908035). pp. 1-9. ISSN 2090-2204

Staunton, Lisa, Jockusch, Harald and Ohlendieck, Kay (2011) Proteomic analysis of muscle affected by motor neuron degeneration: The wobbler mouse model of amyotrophic lateral sclerosis. Biochemical and Biophysical Research Communications, 406 (4). pp. 595-600. ISSN 0006-291X

Mullen, Edel, O'Reilly, Elaine and Ohlendieck, Kay (2011) Skeletal muscle tissue from the Goto-Kakizaki rat model of type-2 diabetes exhibits increased levels of the small heat shock protein Hsp27. Molecular Medicine Reports, 4. pp. 229-236. ISSN 1791-2997

Donoghue, Pamela, Staunton, Lisa, Mullen, Edel, Manning, Gwen and Ohlendieck, Kay (2010) DIGE analysis of rat skeletal muscle proteins using nonionic detergent phase extraction of young adult versus aged gastrocnemius tissue. Journal of Proteomics, 73 (8). pp. 1441-1453. ISSN 1874-3919

Lewis, Caroline, Jockusch, Harald and Ohlendieck, Kay (2010) Proteomic Profiling of the Dystrophin-Deficient MDX Heart Reveals Drastically Altered Levels of KeyMetabolic and Contractile Proteins. Journal of Biomedicine and Biotechnology, 2010 (648501). pp. 1-20. ISSN 1110-7243

Lewis, Caroline and Ohlendieck, Kay (2010) Proteomic profiling of naturally protected extraocular muscles from the dystrophin-deficient mdx mouse. Biochemical and Biophysical Research Communications, 396 (4). pp. 1024-1029. ISSN 0006-291X

Mullen, Edel and Ohlendieck, Kay (2010) Proteomic profiling of non-obese type 2 diabetic skeletal muscle. International Journal of Molecular Medicine, 25 (3). pp. 445-458. ISSN 1107-3756

Gannon, Joan, Doran, Philip, Kirwan, Anne and Ohlendieck, Kay (2009) Drastic increase of myosin light chain MLC-2 in senescent skeletal muscle indicates fast-to-slow fibre transition in sarcopenia of old age. European Journal of Cell Biology, 88 (11). pp. 685-700. ISSN 0171-9335

O'Connell, Kathleen and Ohlendieck, Kay (2009) Proteomic DIGE analysis of the mitochondria-enriched fraction from aged rat skeletal muscle. Proteomics, 9 (24). pp. 5509-5524. ISSN 1615-9853

Doran, Philip, Wilton, Steve D., Fletcher, Sue and Ohlendieck, Kay (2009) Proteomic profiling of antisense-induced exon skipping reveals reversal of pathobiochemical abnormalities in dystrophic mdx diaphragm. Proteomics, 9 (3). pp. 671-685. ISSN 1615-9853

O'Connell, Kathleen, Doran, Philip, Gannon, Joan and Ohlendieck, Kay (2008) Lectin-based proteomic profiling of aged skeletal muscle: Decreased pyruvate kinase isozyme M1 exhibits drastically increased levels of N-glycosylation. European Journal of Cell Biology, 87 (10). pp. 793-805. ISSN 0171-9335

Doran, Philip, O'Connell, Kathleen, Gannon, Joan, Kavanagh, Marcella and Ohlendieck, Kay (2008) Opposite pathobiochemical fate of pyruvate kinase and adenylate kinase in aged rat skeletal muscle as revealed by proteomic DIGE analysis. Proteomics, 8 (2). pp. 364-377. ISSN 1615-9853

Gannon, Joan, Staunton, Lisa, O'Connell, Kathleen, Doran, Philip and Ohlendieck, Kay (2008) Phosphoproteomic analysis of aged skeletal muscle. International Journal of Molecular Medicine, 22 (1). pp. 33-42. ISSN 1107-3756

O'Connell, Kathleen, Gannon, Joan, Doran, Philip and Ohlendieck, Kay (2008) Reduced expression of sarcalumenin and related Ca2+-regulatory proteins in aged rat skeletal muscle. Experimental Gerontology, 43 (10). pp. 958-961. ISSN 0531-5565

Doran, Philip, Gannon, Joan, O'Connell, Kathleen and Ohlendieck, Kay (2007) Aging skeletal muscle shows a drastic increase in the small heat shock proteins aB-crystallin/HspB5 and cvHsp/HspB7. European Journal of Cell Biology, 86 (10). pp. 629-640. ISSN 0171-9335

Doran, Philip, Gannon, Joan, O'Connell, Kathleen and Ohlendieck, Kay (2007) Proteomic profiling of animal models mimicking skeletal muscle disorders. Proteomics Clinical Applications, 1 (9). pp. 1169-1184. ISSN 1862-8346

Donoghue, Pamela, Doran, Philip, Wynne, Kieran, Federsen, Kasper, Dunn, Michael J. and Ohlendieck, Kay (2007) Proteomic profiling of chronic low-frequency stimulated fast muscle. Proteomics, 7 (18). pp. 3417-3430. ISSN 1615-9853

Doran, Philip, Donoghue, Pamela, O'Connell, Kathleen, Gannon, Joan and Ohlendieck, Kay (2007) Proteomic profiling of pathological and aged skeletal muscle fibres by peptide mass fingerprinting (Review). International Journal of Molecular Medicine, 19 (4). pp. 547-564. ISSN 1107-3756

O'Connell, Kathleen, Gannon, Joan, Doran, Philip and Ohlendieck, Kay (2007) Proteomic profiling reveals a severely perturbed protein expression pattern in aged skeletal muscle. International Journal of Molecular Medicine, 20 (2). pp. 145-153. ISSN 1107-3756

Doran, Philip, Martin, Geraldine, Dowling, Paul, Jockusch, Harald and Ohlendieck, Kay (2006) Proteome analysis of the dystrophin-deficient MDX diaphragm reveals a drastic increase in the heat shock protein cvHSP. Proteomics, 6 (16). pp. 4610-4621. ISSN 1615-9853

Doran, Philip, Dowling, Paul, Donoghue, Pamela, Buffini, Maria and Ohlendieck, Kay (2006) Reduced expression of regucalcin in young and aged mdx diaphragm indicates abnormal cytosolic calcium handling in dystrophin-deficient muscle. Biochimica et Biophysica Acta - Proteins and Proteomics, 1764 (4). pp. 773-785. ISSN 1570-9639

Lohan, James, Culligan, Kevin and Ohlendieck, Kay (2005) Deficiency in Cardiac Dystrophin Affects the Abundance of the α-/β-Dystroglycan Complex. Journal of Biomedicine and Biotechnology, 2005 (1). pp. 28-36. ISSN 1110-7243

Donoghue, Pamela, Doran, Philip, Dowling, Paul and Ohlendieck, Kay (2005) Differential expression of the fast skeletal muscle proteome following chronic low-frequency stimulation. Biochimica et Biophysica Acta - Proteins and Proteomics, 1752 (2). pp. 166-176. ISSN 1570-9639

Mulvey, Claire, Harno, Erika, Keenan, Alan and Ohlendieck, Kay (2005) Expression of the skeletal muscle dystrophin–dystroglycan complex and syntrophin-nitric oxide synthase complex is severely affected in the type 2 diabetic Goto–Kakizaki rat. European Journal of Cell Biology, 84 (11). pp. 867-883. ISSN 0171-9335

Lohan, James and Ohlendieck, Kay (2004) Drastic reduction in the luminal Ca2+-binding proteins calsequestrin and sarcalumenin in dystrophin-deficient cardiac muscle. Biochimica et Biophysica Acta, 1689 (3). pp. 252-258. ISSN 0925-4439

Dowling, Paul, Doran, Philip and Ohlendieck, Kay (2004) Drastic reduction of sarcalumenin in Dp427 (dystrophin of 427 kDa)-deficient fibres indicates that abnormal calcium handling plays a key role in muscular dystrophy. Biochemical Journal, 379 (Pt.2). pp. 479-488. ISSN 0264-6021

Glover, Louise and Ohlendieck, Kay (2004) Illustration of Skeletal Muscle Calsequestrin Complex Formation by Cell Overlay and Two-Dimensional Blot Overlay Methodology. Basic and Applied Myology, 14 (4). pp. 231-241. ISSN 1120-9992

Glover, Louise, Heffron, James J.A. and Ohlendieck, Kay (2004) Increased sensitivity of the ryanodine receptor to halothane-induced oligomerization in malignant hyperthermia-susceptible human skeletal muscle. Journal of applied physiology, 96 (1). pp. 11-18. ISSN 8750-7587

Dowling, Paul, Doran, Philip, Lohan, James, Culligan, Kevin and Ohlendieck, Kay (2004) Naturally Protected Muscle Phenotypes: Development of Novel Treatment Strategies for Duchenne Muscular Dystrophy. Basic and applied myology : BAM, 14 (3). pp. 169-177. ISSN 1120-9992

Doran, Philip, Dowling, Paul, Lohan, James, McDonnell, Karen, Poetsch, Stephan and Ohlendieck, Kay (2004) Subproteomics analysis of Ca2+-binding proteins demonstrates decreased calsequestrin expression in dystrophic mouse skeletal muscle. European Journal of Biochemistry, 271 (19). pp. 3943-3952. ISSN 0014-2956

Ohlendieck, Kay, Harmon, Shona, Koll, Michael, Paice, Alistair G. and Preedy, Victor R. (2003) Ca2+-Regulatory Muscle Proteins in the Alcohol-Fed Rat. Metabolism, 52 (9). pp. 1102-1112. ISSN 0026-0495

Dowling, Paul, Lohan, James and Ohlendieck, Kay (2003) Comparative analysis of Dp427-deficient mdx tissues shows that the milder dystrophic phenotype of extraocular and toe muscle fibres is associated with a persistent expression of beta-dystroglycan. European Journal of Cell Biology, 82 (5). pp. 222-230. ISSN 0171-9335

O'Reilly, Clare, Pette, Dirk and Ohlendieck, Kay (2003) Increased expression of the nicotinic acetylcholine receptor in stimulated muscle. Biochemical and Biophysical Research Communications, 300 (2). pp. 585-591. ISSN 0006-291X

Mulvey, Claire and Ohlendieck, Kay (2003) Use of continuous-elution gel electrophoresis as a preparative tool for blot overlay analysis. Analytical Biochemistry, 319 (1). pp. 122-130. ISSN 0003-2697

Dowling, Paul, Culligan, Kevin and Ohlendieck, Kay (2002) Distal mdx muscle groups exhibiting up-regulation of utrophin and rescue of dystrophin-associated glycoproteins exemplify a protected phenotype in muscular dystrophy. Naturwissenschaften, 89 (2). pp. 75-78. ISSN 0028-1042

Culligan, Kevin, Banville, Niamh, Dowling, Paul and Ohlendieck, Kay (2002) Drastic reduction of calsequestrin-like proteins and impaired calcium binding in dystrophic mdx muscle. Journal of applied physiology, 92 (2). pp. 435-445. ISSN 8750-7587

Glover, Louise, Quinn, Sandra, Ryan, Michelle, Pette, Dirk and Ohlendieck, Kay (2002) Supramolecular calsequestrin complex : Protein–protein interactions in chronic low-frequency stimulated muscle, postnatal development and ageing. European Journal of Biochemistry, 269 (18). pp. 4607-4616. ISSN 0014-2956

Culligan, Kevin, Glover, Louise, Dowling, Paul and Ohlendieck, Kay (2001) Brain dystrophin-glycoprotein complex: persistent expression of beta-dystroglycan, impaired oligomerization of Dp71 and up-regulation of utrophins in animal models of muscular dystrophy. BMC Cell Biology, 2 (2). ISSN 1471-2121

Maguire, Patricia and Ohlendieck, Kay (1996) Oligomerization of sarcoplasmic reticulum Ca2+‐ATPase from rabbit skeletal muscle. FEBS Letters, 396. pp. 115-118. ISSN 0014-5793